angioedema

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angioedema

 [an″je-o-ĕ-de´mah]
a localized edematous reaction of the deep dermis or subcutaneous or submucosal tissues appearing as giant wheals; urticaria is the same physiologic reaction occurring in the superficial portions of the dermis.
hereditary angioedema an autosomal dominant disorder of the complement system manifested as recurrent episodes of edema of the skin, upper respiratory tract, and gastrointestinal tract. It may be mediated by such factors as minor trauma, sudden changes in environmental temperature, and sudden emotional stress. adj., adj angioede´matous.

an·gi·o·e·de·ma

(an'jē-ō-ĕ-dē'mă),
Recurrent large circumscribed areas of subcutaneous or mucosal edema of sudden onset, usually disappearing within 24 hours; frequently, an allergic reaction to foods or drugs.

angioedema

(ăn′jē-ō-ĭ-dē′mə)
n.
Rapid swelling of the subcutaneous tissues and submucosal membranes, often accompanied by urticaria.

angioneurotic oedema

(1) Acquired angioedema, a chronic and potentially fatal condition characterised by abdominal pain and episodic localised subcutaneous, periorbital, periocular and laryngeal oedema, due to an absence of C1 esterase inhibitor.
 
Clinical findings
Recurrent oedema; abdominal pain; laryngeal oedema, which may compromise breathing.

Diagnosis
History of recurrent angioedema, abnormally low or absent C1 esterase inhibitor in blood.
 
Triggers
Allergies (e.g., foods, pollen, insect bites); drugs (e.g., ACE inhibitors, salicylates); stress; exposure to cold, water, sunlight or heat.

Management
Epinephrine, antihistamines, corticosteroids (androgens).

(2) Hereditary angioneurotic oedema, see there

angioedema

1. A general term for a vascular reaction of the deep dermis, subcutaneous or submucosal tissues, which corresponds to localized edema 2º to vasodilation and ↑ capillary permeability.
2. Angioneurotic edema, see there.

an·gi·o·e·de·ma

(an'jē-ō-ĕ-dē'mă)
1. Recurrent large circumscribed areas of subcutaneous edema of sudden onset, usually disappearing within 24 hours; seen mainly in young women, frequently as an allergic reaction to foods or drugs.

Angioedema

An allergic skin disease characterized by patches of confined swelling involving the skin the layers beneath the skin, the mucous membranes, and sometimes the viscera—called also angioneurotic edema, giant urticaria, Quincke's disease, or Quincke's edema.

Bannister,

Henry M., U.S. physician, 1844-1920.
Bannister disease - recurrent large circumscribed areas of subcutaneous edema, frequently an allergic reaction to foods or drugs. Synonym(s): angioedema

Quincke,

Heinrich Irenaeus, German physician, 1842-1922.
Quincke capillary pulsation - Synonym(s): Quincke pulse
Quincke disease - Synonym(s): Quincke edema
Quincke edema - recurrent, large, circumscribed areas of subcutaneous edema of sudden onset, usually disappearing within 24 hours. Synonym(s): angioedema; Milton disease; Milton urticaria; Quincke disease; Quincke I syndrome
Quincke meningitis - intracranial hypertension of unknown origin.
Quincke needle
Quincke pulse - capillary pulsation, a sign of arteriolar dilation and especially well seen in severe aortic insufficiency. Synonym(s): Quincke capillary pulsation; Quincke sign
Quincke puncture - a puncture into the subarachnoid space of the lumbar region to obtain spinal fluid for diagnostic or therapeutic purposes. Synonym(s): lumbar puncture
Quincke sign - Synonym(s): Quincke pulse
Quincke spinal needle
Quincke I syndrome - Synonym(s): Quincke edema

an·gi·o·e·de·ma

(an'jē-ō-ĕ-dē'mă)
Recurrent large circumscribed areas of subcutaneous or mucosal edema of sudden onset, usually disappearing within 24 hours; often due to an allergic reaction to foods or drugs.
Synonym(s): angioneurotic edema.

Patient discussion about angioedema

Q. Is severe diarrhea sign of angioedema? I have sudden onset of painful diarrhea with stomach pain.

A. Severe diarrhea can be a sign of angioedema but it is a very unlikely way of angioedema to show, especially if that is the only symptoms and there is no obvious seen swelling of skin or shortness of breath. Stomach ache with diarrhea is usually caused by an infection, most likely a viral infection, and should pass within a few days. If symptoms are unbarable or continue, you should see your doctor.

Q. What can cause an angioedema on 15 year old girl? I’ve been getting angioedema signs on my left arm for the past few weeks, not severe but it itches and sure don’t help my low-as-it-is self esteem…

A. The following may cause angioedema -

Animal dander
Certain medications (drug allergy)
Emotional stress
Exposure to water, sunlight, cold or heat
Foods (such as berries, shellfish, nuts, eggs, milk, other)
Insect bites
Pollen

Hives or angioedema may also occur after an illness or infection.
Try to see if you were exposed to any of this and report it to your Dr.


More discussions about angioedema
References in periodicals archive ?
Despite a positive family history of angioedema attacks, a long history of recurrent peripheral and abdominal attacks, and more than 100 laryngeal attacks, the patient was only diagnosed with HAE at age 50 (Table 1).
Gastrointestinal tract involvement is an important feature, often the most common symptom missed in HAE. Crampy and colicky abdominal pain is present in 43-93% of cases [5].
This study was designed to determine the prevalence and occurrence of clinical manifestations of hereditary angioedema (HAE) in previously unevaluated blood relatives of known (index) patients with HAE in a few villages of a city in a province (Duzce) in Turkey.
Antioxidant activity of HAE Solanum xanthocarpum was performed invitro by free radical scavenging method (12) .2,2-diphenyl-1-picrylhydrazyl DPPH(Sigma), ascorbic acid(Merk) Butylated hydroxyl toluene (BHT) and other chemical of analytical grade was used.
A diagnosis of HAE type II was established based on clinical and laboratory findings with sensitivity to estrogen hormone as symptoms were triggered and worsened by OCP intake, menstruation, and pregnancy.
When administered at the onset of HAE attack symptoms at the recommended dose, RUCONEST works to return a patient's C1-INH levels to normal range and quickly begins to relieve the symptoms of an HAE attack with a low recurrence of symptoms.
HAE is a rare and debilitating genetic disease with an estimated prevalence of 1 in 50,000.
According to the decreased serum C1-INH and C4 concentration the patient was finally diagnosed with HAE type I.
deal, which is reported to hae required Real pay 10million euros (PS7.9m) to Leante to actiate the keeper's release clause, could hae ramications for Madrid stopper Diego Lopez.
"2014 marks the 40th anniversary for HAE and we are keen to shout about the success of UK hire and our contribution to the economy.
The prestigious certification was awarded after a rigorous inspection which included a detailed desktop audit of A-Plant's Performance Standards Department and 11 Service Centres which were randomly selected by the HAE to represent a crosssection of the business, to ensure they met its stringent Safety and Quality criteria.
HAE is important to otolaryngologists because its most serious consequence is edema of the mucosa of the upper airway that can lead to severe airway obstruction and even death.