DYRK1A

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DYRK1A

A gene on chromosome 21q22.13 that encodes a member of the dual-specificity tyrosine-phosphorylation-regulated kinase (DYRK) family, which catalyses its autophosphorylation on serine/threonine and tyrosine residues. DYRK1A may play a key role in a signalling pathway that regulates cell proliferation and may be involved in brain development. 

Molecular pathology
DYRK1A is a candidate gene for learning defects associated with Down syndrome.
References in periodicals archive ?
Other projects in delivery include a GBP3 million Fleet Helicopter Support Unit (FHSU) for the Defence Infrastructure Organisation at HMNB Devonport, the largest naval base in Western Europe.
The notice says: "Additional Training Services including: Move of the Submarine Training in HMS Raleigh to HMNB Clyde to form the Future Submarine School (FSS) relocating, modernising supporting the resulting training and equipment delivery and support in the new facility." The successful contractor will also provide training to the Royal Marines and manage "military assets, equipment, documentation" and a "cadre of Naval Service instructors".
The new minister is a Royal Navy reservist, a former minister for the armed forces and the MP for Portsmouth, home of HMNB Portsmouth.
Linwood man Jonathan Parkhill, 33, pocketed almost PS14,000 from his scheme, which involved him nicking food, clothing and equipment from a stores facility at HMNB Clyde.
Crew greet their families waiting on the jetty alongside HMS Queen Elizabeth as she returns to HMNB Portsmouth after 114 days away at sea Matt Cardy
ABB, a leading technology company, said its new shore-to-ship technology minimises environmental impact and secures reliable electricity to Her Majesty's Naval Base (HMNB) Portsmouth in the UK.
About 600 demonstrators holding banners and waving CND flags and Saltires walked from the peace camp at Faslane in Argyll to the gates of HMNB Clyde, where the country's nuclear submarines are based.
Visitors will be required to carry valid ID (NICOP / Pakistani Passport) and use 'Victory Gate' of HMNB Ports Mouth for gaining access to the ship.
<B The ship's company from HMS Ocean form a guard of honour during the decommissioning ceremony for HMS Ocean attended by the Queen at HMNB Devonport in Plymouth yesterday
HM Coastguard and North Yorkshire Police attended the incident alongside a Royal Navy bomb disposal unit from the HMNB Clyde site at Faslane, Scotland.