KIF2A

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KIF2A

A gene on chromosome 5q12-q13 that encodes a microtubule-associated motor protein required for normal brain development, which may regulate microtubule dynamics during axonal growth. KIF2A is required for normal progression through mitosis for normal congress of chromosomes at the metaphase plate, and is also required for normal spindle dynamics during mitosis. KIF2A promotes spindle turnover and is implicated in formation of bipolar mitotic spindles. It has microtubule depolymerisation activity.

References in periodicals archive ?

Besides PSA, detecting a panel of other biomarkers, such as hk2, urokinase Plasminogen Activator (uPA) and its receptor (uPAR), TGF[beta], IL6, IL6R, Ki-67, ERK5, and DRE may improve PCa diagnosis, staging, prognosis and monitoring (4).

Characterization of Monoclonal and Polyclonal Antibodies Recognizing Prostate Specific Antigen: Implication for Design of a Sandwich ELISA

Total PSA, serbest PSA, iPSA ve hK2 gibi prostat kokenli 4 kallikrein proteinin serum duzeyleri olculur.

Prostat Kanserinde; Uriner, Serum ve Doku Biyomarkerlerinde Yeni Gelismeler Nelerdir?/What are the New Developments in Urinary, Serum and Tissue Biomarkers in Prostate Cancer?

(24-30) Salicinium's mechanism also involves the endoplasmic reticulum and the HK2 pathway.

Salicinium--disrupting anaerobic glycolosis and improving GcMAF immune response

Among them, some members of the "two-component signal transduction system" gene group (tcsA, phkB, hk2, hk8-2, hk-8-3, and hk-8-6) (Table 2, Supplementary Table 5) are particularly interesting.

Transcriptome-Based Modeling Reveals that Oxidative Stress Induces Modulation of the AtfA-Dependent Signaling Networks in Aspergillus nidulans

Human kidney epithelial (HK2) cells were obtained from ATCC (Manassas, Virginia, USA).

miR-382 Contributes to Renal Tubulointerstitial Fibrosis by Downregulating HSPD1

HK2, PDK4, and CS regulate glycolysis, acetyl-CoA generation, and tricarboxylic acid cycle (TCA cycle), respectively.

Qiliqiangxin Enhances Cardiac Glucose Metabolism and Improves Diastolic Function in Spontaneously Hypertensive Rats

HG Promotes CD36 Expression in a Time-Dependent Manner, While NG Has No Effect on CD36 Expression in HK2 Cells.

High Glucose Promotes CD36 Expression by Upregulating Peroxisome Proliferator-Activated Receptor [gamma] Levels to Exacerbate Lipid Deposition in Renal Tubular Cells

Each image is decomposed into two low frequency coefficients (La1, La2) to (Lk1, Lk2) and some high frequency coefficients (Ha1, Ha2, ..., Han) to (Hk1, Hk2, ..., Hkn).

Multifocus Image Fusion in Q-Shift DTCWT Domain Using Various Fusion Rules

The 4Kscore measures the blood plasma levels of four different prostate-derived kallikrein proteins - Total PSA, Free PSA, Intact PSA and Human Kallikrein-2 (hK2).

Journal features encouraging results from multi-institutional study of Opko Health's 4Kscore Test for high grade prostate cancer

Determination and analysis of antigenic epitopes of prostate specific antigen (PSA) and human glandular kallikrein 2 (hK2) using synthetic peptides and computer modeling.

Serum Concentrations of Prostate-Specific Antigen Measured Using Immune Extraction, Trypsin Digestion, and Tandem Mass Spectrometry Quantification of LSEPAELTDAVK Peptide

According to Hong Kong banking statistics, international claims and liabilities of Hong Kong banks were HK 9.5 trillion [dollars] and HK 7.2 trillion [dollars] respectively, resulting in HK2.3 trillion [dollars] of net foreign claims as of June 2014.

The monetary stimulus illusion: the record in China, Japan, and even the United States is one of disappointment if not failure

The role of molecular forms of prostate-specific antigen (PSA or hK3) and of human glandular kallikrein 2 (hK2) in the diagnosis and monitoring of prostate cancer and in extra-prostatic disease.