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Moreover, the peak was unique to hK4 in that it did not coincide with the peaks measured for other kallikreins (hK2, hK11, and hK3) known to be present in seminal plasma at concentrations much higher than that of hK4.
We further measured hK5, hK6, and hK11 protein (a previously identified prostate and ovarian cancer biomarker) (24) in the same set of patients and controls, as above.
In the present study, we monitored the effects of hormone treatment on serum and urine concentrations of hK2, hK3, hK4, hK5, hK6, hK7, hK8, hK10, hK11, hK13, and hK14 in female-to-male transsexuals receiving high-dose testosterone treatment for 4-12 months.
In this study, we examined the effect of hormone treatment on serum and urine concentrations of hK2 to hK8, hK10, hK11, hK13, and hK14, obtained from male-to-female transsexuals who were receiving combined estrogen and antiandrogen therapy.
The markers approved for prevalidation were human kallikrein 2 (hk2), hk4, hk11, thrombospondin 1, percent [-2]proPSA, and EPCA2 (early prostate-specific antigen 2).
AN army-issue HK11 machine gun and a TV were stolen from a 34-year-old man's home in Valadinou street, Larnaca it emerged on Wednesday.
8 cents (Year ended 31 December 2008: Basic earnings pershare of HK11.
She was the first to purify and functionally characterize hK6 and hK10 from ovarian cancer ascites fluid and hK11, a candidate prostate cancer biomarker, from seminal plasma.
Because the hK4, hK6, hK8, and hK11 proteins are produced by more restricted tissues (12, 21-23), hK7 might play more general roles than other human kallikreins, including the degradation of adhesion molecules between cells (24).
Because the KLK8 gene is predicted to encode for a secreted serine protease, this enzyme may have value as a biomarker, similar to hK3 (PSA) (3), hK6, hK10 (NES1), and hK11 (TLSP) (4-7).
Recombinant hK1, hK2, hK3, hK4, hK5, hK6, hK7, hK8, hK9, hK10, hK11, hK12, hK14, and hK15 proteins did not produce measurable readings, even at concentrations 1000-fold higher than that of hK13.
New gene Previous gene New protein symbol (a,b) symbol(s) symbol KLK1 KLK1 hK1 KLK3 KLK3 hK3 KLK2 KLK2 hK2 KLK4 PRSS17, KLK-L1, KLK4 hK4 KLK5 KLK-L2 hK5 KLK6 PRSS9 hK6 KLK7 PRSS6 hK7 KLKS PRSS19 hK8 KLK9 KLK-L3 hK9 KLK10 PRSSL1, hK10 KLK11 PRSS20 hK11 KLK12 KLK-L5 hK12 KLK13 KLK-L4 hK13 KLK14 KLK-L6 hK14 New gene symbol (a,b) Other protein names/symbols KLK1 Pancreatic/renal kallikrein, hPRK KLK3 Prostate-specific antigen, PSA KLK2 Human glandular kallikrein 1, hGK-1 KLK4 Prostase, KLK-L1 protein, EMSP1 KLK5 KLK-L2 protein, HSCTE KLK6 Zyme, protease M, neurosin KLK7 HSCCE KLKS Neuropsin, ovasin, TADG-14 KLK9 KLK-L3 protein KLK10 NES1 protein KLK11 TLSP/hippostasin KLK12 KLK-L5 protein KLK13 KLK-L4 protein KLK14 KLK-L6 protein New gene GenBank symbol (a,b) Accession No.
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