hCG


Also found in: Dictionary, Thesaurus, Acronyms, Encyclopedia, Wikipedia.

gonadotropin

 [go´nah-do-tro″pin]
any hormone having a stimulating effect on the gonads. Two such hormones are secreted by the anterior pituitary gland: follicle-stimulating hormone and luteinizing hormone, both of which are active, but with differing effects, in the two sexes. Called also gonadotropic hormone.
chorionic gonadotropin (human chorionic gonadotropin (HCG) (hCG))
1. a glycopeptide hormone that is produced by cells of the fetal placenta and maintains the function of the corpus luteum during the first few weeks of pregnancy. It is thought to promote steroidogenesis in the fetoplacental unit and to stimulate fetal testicular secretion of testosterone. It can be detected by immunoassay in the maternal urine within days after fertilization; this provides the basis for the most commonly used pregnancy test.
2. the same principle obtained from the urine of pregnant women, used in treatment of certain cases of cryptorchidism and male hypogonadism, to induce ovulation and pregnancy in certain infertile, anovulatory women, and to increase the numbers of oocytes for patients attempting conception using assisted reproductive technologies such as gamete intrafallopian transfer or in vitro fertilization; administered intramuscularly. See also choriogonadotropin alfa.

HCG

, hCG

HCG

abbr.
human chorionic gonadotropin

hCG

Human choriogonadotropic hormone A dimeric glycoprotein hormone synthesized and secreted by the placenta composed of a 92 amino acid α subunit similar to pituitary hormones–TSH, FSH and LH, and a unique 145 amino acid β-subunit linked to lactose and hexosamine that is produced by the syncytiotrophoblast; the β subunit is an early marker for pregnancy; in the fetal liver and kidney, and certain tumors; hCG is released in a pulsatile fashion in normal pregnancy, peaks at the 10th gestational wk with serum levels of 50-140 000 IU/L, later falling to 10-50 000 IU/L2; hCG may be low to undetectable in ectopic pregnancy or ↑↑ ↑ in multiple gestation, polyhydramnios, eclampsia, erythroblastosis fetalis or trophoblastic disease–eg, hydatidiform mole, choriocarcinoma and placental site trophoblastic tumor; hCG levels may be ↑↑↑ in tumors producing either the β subunit or both α & β subunits, measured by ELISA or RIA

hCG

Abbreviation for human chorionic gonadotropin.

HCG (human chorionic gonadotrophin)

a HORMONE secreted by the TROPHOBLAST of the developing foetal tissues. It maintains the CORPUS LUTEUM during the first three to four months in pregnancy, thus ensuring a supply of PROGESTERONE for maintaining the uterus lining and preventing MENSTRUATION. HCG begins to be secreted as soon as the trophoblast implants in the uterine wall and it is at its highest concentration between the 7th and 10th weeks of pregnancy. The urine of women in the first month of pregnancy contains enough HCG for this to be easily detected by chemical means (the ‘pregnancy test’). After reaching its peak, HCG falls to low concentrations and its only known function is to stimulate the production of TESTOSTERONE by the testes of the male foetus. HCG has almost the same combined properties as LH and LUTEOTROPIC HORMONES.

Human chorionic gonadotropin (hCG)

A hormone excreted during the development of an embryo or fetus.

Patient discussion about hCG

Q. Does a slow rise in HCG hormone during pregnancy a condition to worry? My wife is in second trimester of pregnancy and had a HCG test, which shows fewer levels as compared to previous results. Does a slow rise in HCG hormone during pregnancy a condition to worry?

A. When you have a hCG test in the start of pregnancy, the level of hCG in your blood must increase to double in 2-3 days. While the hCG doubling time will slow down from the mid of the first trimester and hCG level also begin to slowly reduce from 4th month onwards. Thus at this stage there is nothing to worry about, it is normal.

More discussions about hCG
References in periodicals archive ?
The serum specimen was taken from the patients on the morning of the hCG administration day, and the LH, progesterone, and estradiol (E2) measurements were performed.
Strong positivity for hCG (Figure 1) was detected in 90.9% (n=50/55) of cases, whereas 4.9% (n=5/55) of cases showed no staining for hCG.
Quadruple biomarkers (Inh A, hCG, AFP and uE3) results were used to assess median values for normal and healthy population, which would be used in future for calculation of MoM (Multiple of Median) by using formula MoM=Patient result/Lab median, to predict the risk of Down Syndrome.
The aim of this review is to critically appraise the main evidence regarding hCG assays suitable for detection/ monitoring of testicular GCTs, considering the differences between recommendations by CPGs and laboratory practice.
Fuh et al.'s investigated the time-related manner between spontaneous endogenous luteinizing hormone surge, hCG administration, and pregnancy rates in IUI cycles (20).
HCG 21 lies about 1[degrees] north of Tau ([tau]) Eridani and is comprised of five well-separated members.
Significantly higher levels of E2 on hCG day both in clinical and ongoing pregnancies also support the higher chance of pregnancy in patients with good response to ovarian stimulation.
To begin with, HCG is looking to open an oncology laboratory in Oman by early 2018, while it takes a minimum of two years to set up a comprehensive cancer centre.
To address the growing need for expertise and quality medical services in Eastern Africa, HCG CC Cancer Centre will be offering cancer care with multi-disciplinary approach through specialist doctors in Medical, Surgical and Radiation Oncology and a team of experienced clinicians .
The condition is diagnosed by a transvaginal ultrasound and elevated hCG, as recommended by the American Congress of Obstetricians and Gynecologists (2 , 3).
A 51-year-old woman body builder with a many-year history of RA had utilized HCG for weight loss and athletic performance in the past and noted that her joint pain improved.