guanidine


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Related to guanidine: guanidinium

guan·i·dine

(gwahn'i-dēn, -din),
A strongly basic compound, usually found (in some plants and lower animals) as the hydrochloride; a constituent of creatine and arginine.

guanidine

(gwä′nĭ-dēn′)
n.
A strongly alkaline crystalline compound, NHC(NH2)2, formed by the oxidation of guanine and found in the urine as a normal product of protein metabolism. It is commonly used in the organic synthesis of plastics, resins, and explosives.
References in periodicals archive ?
This report provides in depth study of "Guanidine Market" using SWOT analysis i.e.
(21) In addition to the membrane disorganization and pore formation, (21) guanidine compounds have shown to affect DNA and cellular proteins in Gram-positive and Gram-negative bacteria.
However, it is reasonable to assume that the order of the exchange rates for these metabolites would remain the same, with the amino acid the highest and the amide and guanidine much slower.
The compound 4d was obtained from reactions of the guanidine and the 4-formylbenzaldehyde in DMF/NaHCO3 at 70oC (Scheme-3).
coli BL21 (DE3) cells induced with 1mM IPTG were disrupted in lysis buffer (pH 8.0) containing 6 M guanidine hydrochloride and supplemented with 16 mM imidazole at room temperature for 2 h and the recombinant protein was purified by Ni-NTA affinity chromatography.
Phenol-Chloroform-Thiocyanate Guanidine (Brazol, LabTrade, Brazil) DNA Extraction.
Stock solution of polyhexamethylene guanidine hydrochloride (PHMG) (7.5% w/w solution) was prepared by dissolving weighted portion of BIOPAG-D reagent (Institute of Ecotechnological problems, Moscow, Russian Federation) in deionized water.
Finally, the compound (7) was treated with ethylacetate saturated with HCl (gas) to remove all the Boc groups of the guanidine moieties to yield compound (8) as hydrochloride salts.
A gain-of-function mutation replaces a guanidine base with a thymine base, resulting in a valine-to-phenylalanine alteration, [2] and consequently constitutive tyrosine kinase activity along with enhanced proliferation of myeloid cells.
This can be overcome by adding guanidine or glucoprotamin components to the quats, which also helps in removing yeasts and molds.
The amine and guanidine end-groups of PHMG were used for ring-opening polymerization (ROP) of caprolactone for joining antibacterial PHMG block to PCL.

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