GAS6

(redirected from growth arrest-specific 6)

GAS6

A gene on chromosome 13q34 that encodes a ligand for tyrosine-protein kinase receptors AXL, TYRO3 and MER, whose signalling is implicated in cell growth and survival, cell adhesion, cell migration, endothelial cell survival during acidification by preventing apoptosis, optimal cytokine signalling during NK cell development, hepatic regeneration, neuron survival and migration, platelet activation, and regulation of thrombosis.
Mentioned in ?
References in periodicals archive ?
Growth arrest-specific 6 (Gas6) is a secreted vitamin K-dependent protein present in the human circulatory system [8, 9].
Shieh, "Plasma protein growth arrest-specific 6 levels are associated with altered glucose tolerance, inflammation, and endothelial dysfunction," Diabetes Care, vol.
Indeed, a polymorphism in the growth arrest-specific 6 (GAS6) [5] gene was found to be associated with stroke (8), for which male sex is a risk factor (9).

Full browser ?