GADD45A(redirected from growth arrest and DNA damage-inducible protein GADD45 alpha)
GADD45AA gene on chromosome 1p31.2 that is upregulated in response to stressful growth-arrest conditions and exposure to DNA-damaging agents. The encoded protein activates the p38/JNK pathway via MTK1/MEKK4 kinase.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.