DDIT3(redirected from growth arrest and DNA damage-inducible protein GADD153)
DDIT3A gene on chromosome 12q13.1-q13.2 that encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors, which form heterodimers with other C/EBP members—e.g., C/EBP and LAP—preventing their DNA binding activity. DDIT3 is activated by endoplasmic reticulum stress, and plays roles in adipogenesis, erythropoiesis and apoptosis.
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