growing teratoma syndrome

growing teratoma syndrome

A rare condition seen in non-seminomatous germ-cell tumours, which is characterised by enlarging metastatic masses despite appropriate systemic chemotherapy and normalised serum markers.

Management
Interferon is mostly ineffective. Surgery is the cornerstone of therapy and should be performed as soon as possible, as delays can lead to inoperable disease and locally advancing tumours can cause severe renal, biliary, duodenal or large vessel obstruction with bowel necrosis and urinary fistula, potentiating intraoperative and post-operative complications (e.g., ileus, acute pancreatitis, chylous ascites and sepsis).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Growing teratoma syndrome (GTS) is a rare complication of ovarian germ cell tumours and occurs in young age group.
Growing teratoma syndrome (GTS) is a rare clinical entity first described by Logothetis et al in 1982.
Growing teratoma syndrome after ovarian germ cell tumours.
However, tumor recurrence has been reported through a phenomenon known as "growing teratoma syndrome," which is extremely rare and refers to a relapse of malignancy due to partial response to surgical resection or chemotherapy [18].
Growing teratoma syndrome (GTS) is thought to be the progression of immature to mature teratoma during or following chemotherapy.
Lhomme, "Growing teratoma syndrome after ovarian germ cell tumors," Obstetrics and Gynecology, vol.
Anesthetic management in a patient with giant growing teratoma syndrome: A case report.
Growing Teratoma Syndrome of the Ovary: Review of Literature and first Report of a Carcinoid Tumor Arising in a Growing Teratoma of the Ovary; Am J Surg Path.
The impression made at this time was either a growing teratoma syndrome or a sarcoma element that was non- responsive to chemotherapy.
As the tumour markers (CA-125, beta-human chorionic gonadotrophin and alpha-fetoprotein) were within the normal range, a working diagnosis of growing teratoma syndrome (GTS) of the ovary was made.
Growing teratoma syndrome and peritoneal gliomatosis.
Growing teratoma syndrome is the recurrence of benign mature teratoma tissue after the treatment of immature malignant teratoma.