group sequential design

group sequential design

A clinical trial design rgat allows one to examine the data at specific time points or after a defined number of patients have been entered and followed up, based on a stopping rule derived from repeated significance tests.
References in periodicals archive ?
It covers different types of designs, from group sequential design to early-phase oncology trials, as well as adaptive trial monitoring and advanced features of the software such as data generation and toolkits.
It covers statistical methods for various adaptive designs such as adaptive group sequential design, adaptive dose-escalation design, adaptive seamless phase II/III trial design, and biomarker-adaptive design.