In another study assessing the long term visual outcome of the modified grid laser photocoagulation for the diffuse DME by Lee et al  it was seen that three years after initial grid treatment the visual acuity improved in 14.5%, remained unchanged in 60.9% and worsened in 24.6% of the eyes.
We report the results of 27 eyes with diffuse DME treated with intravitreal bevacizumab followed by grid laser photocoagulation. Results revealed both anatomical and functional improvement [Figure 2 A and B].
Wu et al., "Intravitreal bevacizumab plus grid laser photocoagulation
or intravitreal bevacizumab or grid laser photocoagulation
for diffuse diabetic macular edema: results of the Pan-american Collaborative Retina Study Group at 24 months," Retina, vol.
A carefully designed prospective randomized trial conducted by the Diabetic Retinopathy Clinical Research Network (DRCR.net) investigated the efficacy and safety of 1-mg and 4-mg doses of preservative-free intravitreal TA (Trivaris) in comparison with focal or grid laser photocoagulation
Demirok, "Comparison between intravitreal triamcinolone with grid laser photocoagulation
versus bevacizumab with grid laser photocoagulation
combinations for branch retinal vein occlusion," ISRN Ophthalmology, vol.
In regard to the number of IVB treatments, previous studies have shown that additional grid laser photocoagulation for recurrent ME in BRVO after IVB treatment may reduce the number of IVB treatments [23, 24].
Considering these results and the potential side effects, such as induction of scotoma by grid laser photocoagulation, retreatment with IVB alone might be a feasible option for recurrent or persistent ME secondary to BRVO only.
(33) Of these 728 Eyes, 155 (21%) had macular edema reducing visual acuity to 20/50 or worse (group M eyes, macular edema) The group M arm of the CVOS evaluated the treatment of macular edema in CRVO with grid laser photocoagulation
in 155 eyes (77 treated eyes and 78 control eyes) over a 3-year followup period.
Macular edema is one of the most important causes of impaired vision in patients with branch retinal vein occlusion (BRVO), and, in 1984, the Branch Vein Occlusion Study (BVOS) group demonstrated the efficacy of grid laser photocoagulation
to improve visual acuity in patients with macular edema secondary to BRVO .
* Timely focal and grid laser photocoagulation
helps in improving and stabilizing the visual acuity in patients with diabetic macular edema.
The standard therapy for visual impairment caused by DME is focal and/or grid laser photocoagulation
. However, this usually simply stabilizes vision.