Further, haemophagocytic histiocytes were observed with a decrease in erythropoietic and granulopoietic
cells, while megakaryocytes were rarely observed (Figure).
Bradstock, "G-CSF: from granulopoietic
stimulant to bone marrow stem cell mobilizing agent," Cytokine & Growth Factor Reviews, vol.
Saeland et al., "Potentiation of early hematopoiesis by tumor necrosis factor-alpha is followed by inhibition of granulopoietic
differentiation and proliferation," Blood, vol.
Toxic effects of benzene and benzene metabolites on granulopoietic
stem cells and bone marrow cellularity in mice.
effects of lithium on human bone marrow in vitro.
Examination of the bone marrow from alcoholic patients has shown vacuolated granulopoietic
progenitors with a significantly reduced number of mature granulocytes (Yeung et al.
Visual examination of spleen sections revealed that splenocytes from NOD mice had a tendency to ring-shaped rather than polylobed morphology, indicating presence of granulopoietic
stage 1 myeloblasts.
Reduction of Hb and TLC might be due to interference in metabolism, suppression of the granulopoietic
activity of bone marrow by residual toxicants (Ianchev, 2001; Rana et al., 2008), increased rate of destruction or reduction in rate of formation of erythrocytes and altered cellular composition of blood leading to anemia, anisocytosis, eosinophilia and leucopenia and also due to impaired absorption of folic acid (Hardman and Limbird, 1996) and disruption of liver biosynthesis of heme (Woods and Fowler, 1986).
Suppression of granulopoietic
progenitor cell proliferation by metabolites of the branched-chain amino acids.
organs of Mustelus schmitti (Chondrichthyes, Triakidae): a light and electron microscopic study.
Differential responses of early erythropoietic and granulopoietic
progenitors to dexamethasone and cortisone.