granulomatous mastitis


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gran·u·lom·a·tous mas·ti·tis

a rare granulomatous inflammation of lobular breast tissue, with multinucleated giant cells; sarcoidosis is excluded by the frequent presence of neutrophils and absence of involvement of other tissues.

granulomatous mastitis

A rare inflammatory disease of the breast, often presenting as a tender mass. Symptoms usually appear within two years after a pregnancy. Even with mammography or ultrasonography, granulomatous mastitis may be difficult to distinguish from breast cancer without biopsy. Once the diagnosis is definitively established, the disease is treated with corticosteroids or by surgical removal of the mass.
See also: mastitis
References in periodicals archive ?
The records of 51 female patients who clinically and pathologically diagnosed with granulomatous mastitis were evaluated in detail.
Granulomatous mastitis complicated by arthralgia and erythema nodosum successfully treated with prednisolone and methotrexate.
Granulomatous mastitis: diagnosis by ultrasound-guided core biopsy.
Ozkan, "Aetiology of idiopathic granulomatous mastitis," World Journal of Clinical Cases, vol.
Hisham, "Chronic granulomatous mastitis: diagnostic and therapeutic considerations," World Journal of Surgery, vol.
In patients with granulomatous mastitis, the lesions tended to be large, irregular, dispersed, and always had abundant blood supply.
Multimodality imaging features of idiopathic granulomatous mastitis: outcome of 12 years of experience.
Of the two cases that were labeled as granulomatous mastitis, one patient had excision of mass and HPE confirmed a nontuberculous granulomatous mastitis.
Nisheena, "Idiopathic granulomatous mastitis: a rare entity with a variable presentation," Breast Diseases, vol.
A diagnosis of granulomatous mastitis was established by histopathological examination showing the presence of numerous epithelioid cells as well as the multinucleated Langerhans-type giant cells, neutrophils, lymphocytes, and stromal cells in the FNAB samples and the presence of an exclusively granulomatous inflammatory reaction with neither caseous necrosis nor any specific organism in the samples obtained by other biopsy methods.
On the basis of the clinico-histological findings, a diagnosis of borderline- lepromatous leprosy with granulomatous mastitis was made.
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