granulomatous disease


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chron·ic gran·u·lom·a·tous dis·ease

a congenital defect in the killing of phagocytosed bacteria by polymorphonuclear leukocytes, which cannot increase their oxygen metabolism due to dysfunctional NADPH oxidase, either because of defective cytochrome [MIM*233710 and MIM*233690] or other specific factor deficiencies [MIM*233700 and MIM*306400]. As a result there is an increased susceptibility to severe infection by catalase-positive microorganisms; inheritance is usually autosomal recessive or X-linked.
Farlex Partner Medical Dictionary © Farlex 2012

granulomatous disease

(1) A nonspecific term for any disease characterised by multiple granulomas.
(2) Chronic granulomatous disease, see there.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

Granulomatous disease

Characterized by growth of tiny blood vessels and connective tissue.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
According to the latest report "Chronic Granulomatous Disease Market 2019 Global Analysis by Diagnosis, Treatment and Region with Forecast To 2023, published by Market Research Future, the Global Chronic Granulomatous Disease Market Analysis Revealing Key Drivers & Growth Trends through 2023
(8, 15, 19) Diffuse nonnecrotizing granulomas are typically seen in granulomatous disease. (8) Foamy histiocytes in the small intestinal lamina propria and nodular hyperplasia complicated by lymphoma of the small bowel have also been reported.
Chronic granulomatous disease (CGD) is a rare inherited primary immunodeficiency disorder.
Chronic granulomatous disease (CGD) is the most common of the primary immunodeficiency in children.
Chronic granulomatous disease (CGD) is a heterogenous genetic primary immune deficiency disorder originating from the defects in nicotinamide adenine dinucleotide phosphate (NADPH) oxidase system, and characterized by life-threatening infections, and granulomas secondary to increased inflammatory responses (1).
Santino and Giovanni were born in October, 2017, with Chronic Granulomatous Disease (CGD), an immune disease in which the immune system does not work properly, meaning even a common cold could become life-threatening, their mother said.
Orchid will also acquire the rights to exclusively license three additional preclinical programmes from Telethon/Ospedale San Rassaele once clinical proof of concept studies for mucopolysaccharidosis type 1 (MPS1 or Hurler syndrome), chronic granulomatous disease (CGD), and globoid cell leukodystrophy (GLD) are complete.
Sarcoidosis is a multisystemic granulomatous disease with a peak onset between the ages of 20 and 40 years.
Nocardia infection in chronic granulomatous disease. Clin Infect Dis 2002; 35: 390-4 [CrossRef]
Lymph node biopsy and pleural biopsy were suggestive of granulomatous disease, without signs of malignancy, leading to a diagnosis of sarcoidosis 1 month later (Fig.

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