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composed of granulomas.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


Having the characteristics of a granuloma.
Farlex Partner Medical Dictionary © Farlex 2012


Having the characteristics of a granuloma.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(gran?yu-lo'ma ) (gran?yu-lo'ma-ta) plural.granulomasplural.granulomata [ granulo- + -oma]
An inflammatory response that results when macrophages are unable to destroy foreign substances that have entered or invaded body tissues. Large numbers of macrophages are drawn to the affected area over 7 to 10 days, surround the target, and enclose it. They in turn are surrounded by polymorphonuclear leukocytes, other immune cells, and fibroblasts. Granulomas are common in many conditions, including leprosy, tuberculosis, cat scratch disease, some fungal infections, and foreign body reactions, e.g., reactions to sutures. granulomatous (gran?yu-lo'ma-tus), adjective See: giant cell; tuberculosis; Wegener granulomatosis
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granuloma annulare

A circular rash with a raised red border, usually found on the hands, knuckles, or arms of young patients. The cause is unknown. The rash often lasts 1 or 2 years and then may disappear spontaneously.
See: illustration

apical granuloma

Dental granuloma.

benign granuloma of the thyroid

A lymphadenoma of the thyroid.

coccidioidal granuloma

A chronic, generalized granuloma caused by the fungus Coccidioides immitis.
See: coccidioidomycosis

dental granuloma

A granuloma developing at the tip of a tooth root, usually the result of pulpitis. It consists of a proliferating mass of chronic inflammatory tissue and possibly epithelial nests or colonies of bacteria. It may be encapsulated by fibrous tissue of the periodontal ligament.
Synonym: apical granuloma; apical periodontitis

eosinophilic granuloma

A form of xanthomatosis accompanied by eosinophilia and the formation of cysts on bone.

granuloma fissuratum

A circumscribed, firm, fissured, fibrotic, benign tumor caused by chronic irritation. It may occur where hard objects such as dentures or the earpieces of glasses rub against the labioalveolar fold or the retroauricular fold. The tumor disappears when the irritating object is removed.

foreign body granuloma

Chronic inflammation around foreign bodies such as sutures, talc, splinters, or gravel.
Synonym: foreign body reaction

granuloma fungoides

Mycosis fungoides.

infectious granuloma

Any infectious disease in which granulomas are formed, e.g., tuberculosis or syphilis. Granulomas are also formed in mycoses and protozoan infections.

granuloma inguinale

A granulomatous ulcerative disease in which the initial lesion commonly appears in the genital area as a painless nodule.


This type of granuloma is caused by a short, gram-negative bacillus, Calymmatobacterium granulomatis, (“Donovan body”).


Erythromycin, trimethoprim-sulfamethoxazole, or tetracyclines are used in treating this disease. Single-dose therapy with intramuscular ceftriaxone or oral ciprofloxacin may be effective.

granuloma iridis

A granuloma that develops on the iris.

lipoid granuloma

A granuloma that contains fatty tissue or cholesterol.

lipophagic granuloma

A granuloma in which the macrophages have phagocytosed the surrounding fat cells.

Majocchi granuloma

Majocchi disease.

malignant granuloma

Hodgkin disease.

pyogenic granuloma

See: lobular capillary hemangioma

granuloma pyogenicum

See: lobular capillary hemangioma

pyrogenic granuloma

See: lobular capillary hemangioma

swimming pool granuloma

A chronic skin infection caused by Mycobacterium marinum.

granuloma telangiectaticum

A very vascular granuloma at any site, but esp. in the nasal mucosa or pharynx.

trichophytic granuloma

Majocchi disease.
Medical Dictionary, © 2009 Farlex and Partners


Resembling a tumor made of granular material.
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
A novel bacterium associated with lymphadenitis in a patient with chronic granulomatous disease.
Chronic granulomatous disease is a rare disorder that often goes undiagnosed.
The records of patients who were diagnosed with granulomatous mastitis based on a histopathological examination were evaluated in detail.
In HIV-positive patients, the odds of being diagnosed with a 'non-cancer' diagnosis (including granulomatous inflammation and pleuritis) were higher than in HIV-negative patients (OR 2.16, 95% CI 1.03-4.51; p=0.040).
The commonest causes of cervical lymphadenopathy are reactive lymphadenitis, granulomatous lymphadenitis and metastatic squamous cell carcinoma.
The boy was a diagnosed case of chronic granulomatous disease, based on nitrobluetetrazoleum test (NBT) and dihydrorhodamine (DHR) assay, since three years of age and his regular medication included Trimethoprim-sulphamethoxazole 5 mg/kg/day in two divided daily doses and Itraconazole 5 mg/kg oral solution once daily.
Histologically, granulomatous cheilitis is characterized by chronic inflammatory reaction consisting of lymphocytes, histiocytes, and tuberculoid granuloma having epithelioid cells and Langerhans giant cells (27).
"The clinical features and genetic mutations of chronic granulomatous disease: results from a reference centre at middle Anatolia."-Genetic counseling [Geneva, SwitzerIand]-24.3 [2012]: 327-335.
Up to one-third of patients with renal dysfunction have granulomatous interstitial nephritis.
It is known that nonspecific granulomatous reactions associated with malignancy are common in cancer patients.
Granulomatous mastitis complicated by arthralgia and erythema nodosum successfully treated with prednisolone and methotrexate.

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