granulomatosis with polyangiitis


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granulomatosis with polyangiitis

A form of AUTOIMMUNE small blood vessel disease in which local masses of cells, blood capillaries and fibrous tissue (granulation tissue) form in the nose, the kidneys, the lungs and the heart. These masses cause local damage and become gangrenous. Symptoms include nose-bleeds, blood in the urine (haematuria) and chest pain. The condition may progress to kidney failure. Formerly known as Wegener's granulomatosis.
Collins Dictionary of Medicine © Robert M. Youngson 2004, 2005