granulocyte transfusion


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granulocyte transfusion

Abbreviation: GTX
The transfusion of mature granulocytic white blood cells for use in infected patients with severe neutropenia (an absolute neutrophil count < 500 cells/mL). GTX is used primarily to treat patients with refractory infections due to neutropenia caused by cancer chemotherapy or stem cell transplantation.
See also: transfusion
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The infection control was achieved by granulocyte transfusions besides abscess drainage and extensive antifungal therapy.
Wolach et al., "Successful treatment of invasive aspergillosis in chronic granulomatous disease by granulocyte transfusions followed by peripheral blood stem cell transplantation," Bone Marrow Transplantation, vol.
Granulocyte transfusions, which are given to neutropenic patients within 24 hours of collection and contain lymphocytes and have been identified as a potential cause of TA-GVHD, were only irradiated per policy in 995 of 2066 organizations (48.2%).
The book also includes discussions of specialized blood products such as leukocyte-reduced blood products, cytomegalovirus-reduced risk blood products, granulocyte transfusions, platelets and platelet pheresis, immunoglobulins, and fibrin sealants.

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