graft rejection


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Related to graft rejection: Graft versus host disease

graft rejection

Rejection Clinical immunology The constellation of defenses mounted by the immune system of the recipient of an allograft–eg kidney, liver, pancreas, etc, which compromise the continued viability of grafted tissue. See Graft.
References in periodicals archive ?
Choi, Functional Characteristics of Peripheral CD4/CD8 Double Positive T Cells as a Specific Biomarker for Graft Rejection in Nonhuman Primate Transplantation Model, School of Medicine/Seoul National University, 2017.
However, in the blood sample taken on the day before a liver biopsy that was performed to confirm graft rejection, the dscfDNA concentrations were markedly increased (BTR12-LONG: 5308 copies/mL and BTR16-LONG: 4868 copies/ mL).
The clinical implication of these findings is not clear because it can, even, be interpreted either as a random laboratory result variation comparable to its biological variation [16] or representing the resultant from the natural course of the kidney transplantation or a statistical consequence from the acute graft rejection episodes observed.
In addition to higher levels of selective chemokines, corneal graft rejection is also associated with upregulated expression of chemokine receptors CCR1, CCR2, and CCR5 [34].
Cabanne et al., "Evaluation of calprotectin level in intestinal content as an early marker for graft rejection," Transplantation Proceedings, vol.
Graft rejection is usually mediated by activity of T-cells, especially cytotoxic T cells.
This report provides comprehensive information on the therapeutic development for Corneal Graft Rejection, complete with comparative analysis at various stages, therapeutics assessment by drug target, mechanism of action (MoA), route of administration (RoA) and molecule type, along with latest updates, and featured news and press releases.
Quality of life (QoL) renal transplant recipients (RTRs) kidney functioning graft rejection cross lagged correlation
The adhering cells have low immunogenicity which minimizes the risk of immune reaction and graft rejection and also eliminates the need for immunosuppressive drugs.
Corneal graft failure is one of the most common causes of performing keratoplasty again.1 When vessels are present on the cornea then chances of graft rejection are very high, and it is considered as a high risk corneal graft surgery.2 This high rate of corneal graft failure in cases of vascularized corneas is because after corneal graft these patient can still develop severe immune reaction against the graft and even immunosuppressive therapy cannot help much in the graft survival in such cases.3