When individual return-to-sport criterion was evaluated, patients who failed to achieve 90 per cent quadricep strength were 84 per cent less likely to suffer an ipsilateral graft failure
but three times more likely to suffer a contralateral ACL injury.
Predictive tools have been developed to assess the donorspecific risk of graft failure
. In 2009 Rao et al.
Late or delayed graft failure
could not be studied.
The funds will be used to advance Symic Bio's disease-modifying osteoarthritis drug, SB-061, into a global Phase 2b trial to be started in the latter half of 2019 as well a global Phase 3 trial evaluating the potential for SB-030 to prevent vein graft failure
in peripheral artery disease in 2020.
Information was also included on the source of the transplanted kidney (eg, ECD, a high-risk donor with multiple comorbidities; standard-criteria donor), and the date of graft failure
The primary endpoint of the study was a composite endpoint of treatment failure (biopsy-proven acute rejection or BPAR, graft failure
, loss to follow up or death) that was evaluated after a 12-month treatment period to demonstrate the non-inferiority of Envarsus compared to Prograf.
Pluristem Therapeutics announced that the FDA has granted Orphan Drug Designation to the Company's PLX cell therapy for the treatment of graft failure
and incomplete hematopoietic recovery following hematopoietic cell transplantation, or HCT.
No patients with severe bleeding had graft failure
. The volume of bleeding had no effect on the tympanoplasty graft outcome (p = 0.38).
(1,2) However, preparing the 15-um-thick Descemet membrane (DM) graft is still a challenging issue and is sometimes complicated by surgeon- or donor-related DM graft tears and graft failure
. Standardized techniques for graft preparation, surgical instruments designed for endothelial keratoplasty, and accumulating experience over time have led to a significant reduction of tissue loss.
The use of haplo HCT in the prior decade was mainly obscured by the high rates of graft failure
, graft-versus-host disease, and infectious complications [4, 5].
Vein graft failure
is associated with further revascularisation procedures, myocardial infarction, and death .
Chow et al., "Increased rates of Descemets Stripping automated endothelial keratoplasty (DSAEK) graft failure
and dislocation in glaucomatous eyes with aqueous shunts," Journal of Ophthalmic and Vision Research, vol.