gouty tophi

gouty tophi

Chalky crystalline nodules of a urate salt which may accumulate in the ear cartilage in gout and break through the skin to appear externally.
References in periodicals archive ?
Skin examination revealed multiple purpuric lesions of varying sizes over both forearms and the dorsum of hands (Figure 1) along with multiple subcutaneous gouty tophi over both 1st toes and the left little linger (Figure 2, 3).
Gouty tophi were not grossly observed in the fascia or muscle, but small tophi (-0.25-0.5 mm) were seen sporadically in the synovial sheaths of the flexor tendons, which can occur after many years in patients with poorly controlled gout [5].
Mechanical blockage within the knee secondary to gouty tophi has been demonstrated as a rare cause of limited ROM and locking symptoms.
AggNETs were proposed to form the basis for gouty tophi [19], a long-described white material that typically appears at the end of acute attacks and is characteristic for the chronic phase of gout (Figure 2) [19, 37].
Ultrasound may also be useful in identifying possible underlying causes such as rheumatoid nodules and gouty tophi. (1)
Although not rare, carpal tunnel syndrome (CTS) caused by gouty tophi is still uncommon according to the literature, (3) and its presence indicates the severity of untreated gouty tophi.
In patients with a long evolution of hyperuricemia and many acute attacks, gout can also be found in a chronic form, having as a main manifestation the gouty tophi (tophus = a friable and porous stone), a tophus being a deposit of small monosodium urate crystals surrounded by inflammatory cells.
On a 3D coloured display gouty tophi were observed, the same feature not always being detected on 3T MRI scan.
According to Perez-Ruiz et al., benzbromarone, used alone or combined with allopurinol, is superior to therapy with allopurinol in reducing gouty tophi [21].
Gouty tophi may produce bony erosions and cystic changes of the adjacent bone resulting in chronically deforming arthritis.
About half of cases involve the big toe, but it can present as gouty tophi (a deposit of monosodium urate crystals in the joints, cartilage, bone, and throughout the body that may break out through the skin), kidney stones, or urate nephropathy.
Lumbar radiculopathy secondary to gouty tophi in the filum terminate in a patient without systemic gout: case report.