gossypol


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

gos·sy·pol

(gos'i-pol),
A toxic principle isolated from the seed of the cotton plant (Gossypium) that reduces sperm count; used in China as an oral male contraceptive.

gossypol

/gos·sy·pol/ (gos´ĭ-pol) a toxin found in cottonseed and detoxified by heating; it has male antifertility properties, apparently having its effects in the seminiferous tubules.

gossypol

An aromatic triterpene derived from cotton (Gossypum hirsutum) seed oil, which is 90% effective in reducing sperm counts to the level of infertility and thus flagged as a possible male contraceptive.
 
Cons
Nephrotoxicity, hypokalaemia; one-fourth become permanently sterile.

gos·sy·pol

(gos'i-pol)
(Gossypium hirsutum) This plant's parts are thought to be of value as a male contraceptive (clinical studies done); other uses are as an antineoplastic and vaginal spermicide. Adverse effects reported include heart failure, hepatotoxicity, nephrotoxicity, and, with oral ingestion of seeds, death by poisoning.
Synonym(s): cotton.
[gossypium, + -ol]

gossypol (gäˑ·s·pōl),

n Latin name:
Gossypium hirsutum; parts used: stalks, roots, seeds; uses: contraceptive, dysmenorrhea, labor inducer; precautions: pregnancy, lactation, children; patients with kidney and liver disease; can cause cardiac failure, nausea, diarrhea, muscle weakness, and paralysis. Also called
American upland cotton and
cotton.

gossypol

toxic phenolic pigment in the glands of seeds of gossypium spp.
References in periodicals archive ?
Microbial fermentation is a viable method for detoxification of gossypol and improvement of nutritional properties of CSK in solid state especially on the improvement of amino-acids content in fermented CSK (2,12,13,14).
El-saidy DMS and MMA Gaber Use of cottonseed meal supplemented with iron for detoxication of gossypol as a total replacement of fishmeal in Nile tilapia, Oreochromis niloticus (L) diets.
Some of the transformed plants exhibited resistance to CLCuV disease and also showed changes in boll size/weight, boll shape, plant type, hairiness, gossypol pigments, etc.
Embryonic survival is reduced if embryos are derived from oocytes of cows with follicles of prolonged dominance, diets containing gossypol or that result in increased concentrations of urea and ammonia in blood, or exposure to heat stress.
In the other study, Xiao-Ya Chen and his colleagues at the Chinese Academy of Sciences in Shanghai used a similar trick to increase the cotton bollworm's sensitivity to gossypol, a defense chemical produced by the cotton plant.
The problem is, cottonseed also contains considerable amounts of a natural toxin, gossypol.
But some Scientists, cautioned that untreated cottonseed meal should not be used as a suitable replacement for soybean meal as it contains gossypol, a substance toxic to rabbit.
In addition, the gossypol in cottonseed meal results in poor egg quality.
Gossypol is a natural toxin that is thought to protect the cotton plant from insect damage.