Mice were allocated into three groups (n = 10) for each sex: (1) intact mice (n = 10), (2) bilaterally gonadectomized (GX) (n = 10) mice, and (3) mice that underwent surgery without gonadectomy
(sham operated) (n = 10).
did not alter E2induced vasodilation in either sex.
It is, therefore, imperative that despite what providers and parents may believe, in most cases, there is no surgical urgency to genitoplasty and gonadectomy
. Eliminating the preconceived notion that surgical decision-making for infants is emergent provides opportunities to listen to the adult community living with DSD and reassess the longstanding traditionalist approach to early genital surgery for intersex infants.
It is important to differentiate the two condition because it is necessary for gender assignment and in AGD 30% patients develop germ cell tumors like dysgerminoma, yolksac tumor, Embryonal carcinoma and hence gonadectomy
is necessary in such cases.
) can be performed by a general surgeon or gynaecologist.
In case the patients decide to be males, then they should be treated with androgen replacement with consideration of extensive genital reconstructive surgery including gonadectomy
to avoid malignant degeneration in the intra-abdominal testes.
in young pigs is a usual practice in swine production worldwide.
Dogs who have undergone a gonadectomy
(a spay or castration) are more likely to die from cancer or autoimmune diseases* Those who still have functional reproduction systems at death are more likely to die from infectious disease or trauma.
The hCG stimulation test and other testis hormone markers can be useful in confirming bilateral anorchia after intraoperative diagnosis or for assuring completeness of gonadectomy
after surgery to avoid malignant degeneration of residual tissue (McEachern, Houle, Garel, & Van Vliet, 2004).
Sex differences in hyperalgesia during morphine infusion: Effect of gonadectomy
and estrogen treatment.
Patient having MGD were assigned male gender with gonadectomy
and accepted it well.
was performed under thiopental anesthesia, and all animals were killed by decapitation.