gonadal dysgenesis


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Related to gonadal dysgenesis: gonadal agenesis, Swyer syndrome, XY gonadal dysgenesis

dysgenesis

 [dis-jen´ĕ-sis]
defective development; see also dysplasia and malformation.
gonadal dysgenesis
1. defective development of the gonads.
2. turner's syndrome and its variants.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

go·nad·al dys·gen·e·sis

defective gonadal development, varying types and degrees of which have been identified, including gonadal aplasia or agenesis, rudimentary gonads, congenitally defective gonads, and true hermaphroditism; the character of the external genitalia, genital ducts, and secondary sexual development are only sometimes uniquely related to a given type of gonadal dysgenesis XO GONADAL DYSGENESIS51 consists of monosomy X with a gonadal streak rather than a true ovary, notably seen in Turner syndrome; XX GONADAL DYSGENESIS51 is an autosomal recessive disorder with a female karyotype, streak gonads, and primary amenorrhea, but with no body features of Turner syndrome; XY GONADAL DYSGENESIS51 is an X-linked disorder associated with a male karyotype and a female habitus, streaked gonads, and absence of secondary sexual characteristics.
Synonym(s): ovarian dysgenesis
Farlex Partner Medical Dictionary © Farlex 2012

gonadal dysgenesis

A condition characterized by underdeveloped or imperfectly formed gonads; the prototypic GD is Turner syndrome–45, X0, which occurs in 1:2-7000 ♀ births Clinical Short stature, webbed neck, cubitus valgus, micrognathia with high arched palate, epicanthal folds, lymphedema of hands and feet, aortic coarctation, renal malformation, osteoporosis, DM, widely spaced nipples, sexual infantilism. See Intersex syndromes.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

go·nad·al dys·gen·e·sis

(gō-nad'ăl dis-jen'ĕ-sis)
Defective gonadal development; types include gonadal aplasia or agenesis, rudimentary gonads, congenitally defective gonads, and true hermaphroditism.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Although ambiguous genetalia was the commonest presentation but CAIS mainly presented with inguinal hernia or primary amenorrhea and partial gonadal dysgenesis presented with delayed puberty and micropenis or hypospadias.
Salakos, "Mixed gonadal dysgenesis in a 45,X neonate with chromosome Y material in the dysgenetic gonad," Journal of Pediatric Endocrinology and Metabolism, vol.
Among DGD cases, partial gonadal dysgenesis was the most frequent, followed by mixed gonadal dysgenesis and ovotesticular DSD.
Other Conditions Associated with Gonadal Dysgenesis Ovotesticular DSD Formerly "true May present as hermaphroditism." fairly "typical" Presence of ovarian male or female and testicular phenotype.
The gonads of XY pure gonadal dysgenesis have a high risk of gonadoblastoma and germ cell tumour, particularly dysgerminoma.
A study in the current issue of the journal Pediatric and Developmental Pathology retrospectively examined gonads from 30 patients with gonadal dysgenesis. Cytogenic analyses were performed, investigating specifically the role of a primitive tissue known as a[euro]oeundifferentiated gonadal tissue.
Hypergonadotropic hypogonadism (Primary ovarian failure) due to unilateral or bilateral gonadal dysgenesis or agenesis had been also described in a few case reports in association with MRKHS.
Children having Gonadal dysgenesis (GD) responding to androgen therapy were also advised male gender.
Differential diagnosis must be conducted with other reasons of amenorrhea primaria (6) that deal with sexual secondary normal characters; the most frequent being: gonadal dysgenesis, androgen insensibility, agenesis of vagina and uterus, vaginal transverse septum, and imperforated hymen.
This "endowment" could include recognized medical disorders such as Marfan Syndrome, which augments height, or gonadal dysgenesis or Turner Syndrome, both of which cause shortness and delay maturation.
laevis exposed to low levels of ATZ under laboratory conditions suffered gonadal dysgenesis (Hayes et al.
This review focuses on 3 selected topics of gynecologic pathology with implications for the practicing surgical pathologist: evaluation of hereditary breast-ovarian cancer syndrome (BRCA1 /BRCA2) mutation-carrier specimens; assessment of microsatellite instability and hereditary nonpolyposis colorectal carcinoma (HNPCC)/Lynch syndrome in endometrial carcinomas; and prophylactic surgery for gonadal dysgenesis.