Lange test(redirected from gold sol test)
an obsolete, nonspecific test for altered proteins in spinal fluid. As originally used by Lange in 1912, the test was thought to be specific for neurosyphilis; however, this proved to be incorrect. Dilutions of spinal fluid are made in saline and to these a colloidal gold solution is added; if altered proteins are present, there is a color change or precipitate formed.
[Carl Lange, Ger. physician, 1883–1953]
An obsolete test for diagnosis of cerebrospinal syphilis by the degree of gold precipitation in varying concentrations of colloidal gold solution and spinal fluid.
Lange,Carl F.A., German biochemist, 1883-1953.
Lange solution - a colloidal gold solution used to demonstrate protein abnormalities in spinal fluid.
Lange test - an obsolete, nonspecific test for altered proteins in spinal fluid. Synonym(s): gold sol test; Zsigmondy test