This suggests that there might be other goitrogens
or factors playing a role besides iodine deficiency that need to be explored.
Antithyroid sulfurated compounds in environmental goitrogens
, Gaitan E, editors.
Iodine metabolism in response to goitrogen
induced altered thyroid status under conditions of moderate and high intake of iodine.
Bromate is a goitrogen
, carcinogen, and a zombifying agent.
Variable effects of goitrogens
in inducing precocious metamorphosis in sea lampreys (Petromyzon marinus).
A questionnaire relating thyroid disorders and goitrogens
was given to them and analysis was done.
1,2) The greater demand for iodine may be due to the goitrogen
load in these subjects.
An additional group was administered the goitrogen
PTU (6-n-propyl-2-thiouracil; Sigma-Aldrich Chemicals GmbH, Steinheim, Germany), which served as a reference control for TH effects.
With daily intake ranging from 6 mg to 180 mg iodine, a success rate as high as 90% was achieved, (3) saving patients' thyroids from radioiodide and the toxic goitrogens
Despite the finding that PCBs uniformly reduce circulating levels of TH in experimental animals, PCBs do not exert effects in experimental animals that are fully consistent with experimentally produced hypothyroidism using goitrogens
such as propylthiouracil (PTU).
1) Patients who used water from wells and municipal plants may be exposed to potassium perchlorate, a very powerful goitrogen
that behaves like fluoride, binding to the halide-binding site of the symporter without itself being symported.
31) Bromide is a goitrogen
and interferes with iodide utilization by the thyroid gland, (32-34) and possibly by the mammary gland also.