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A chronic enlargement of the thyroid gland, not due to a neoplasm, occurring endemically in some localities, especially regions where glaciation occurred and depleted the soil of iodine, and sporadically elsewhere.
Synonym(s): struma, goitre.
[Fr. from L. guttur, throat]


Enlargement of the THYROID GLAND from any cause. This may be due to overactivity of the gland in THYROTOXICOSIS, to HASHIMOTO'S THYROIDITIS, to infective thyroiditis, to DYSHORMONOGENESIS, to cancer of the gland or to iodine deficiency.


an abnormal swelling of the neck due to enlargement of the thyroid gland. This may be because of a lack of iodine in the diet (simple goitre) or to overactivity of the gland (exophthalmic goitre).

goiter, goitre

enlargement of the thyroid gland, causing a swelling in the front part of the neck.

adenomatous goiter
multilobular goiters cause thyroid enlargement in cats.
colloid goiter
is characterized by the presence of a large soft thyroid gland with its glandular space distended with colloid. Most cases occur in neonatal lambs, calves and kids which show a high rate of stillbirths and weakness and a high mortality rate. Enlarged thyroid glands and alopecia are good indicants of the existence of a nutritional deficiency of iodine, the usual cause of goiter in animals.
dyshormonogenetic goiter
an impairment in thyroglobulin synthesis is thought to be the cause of inherited, congenital goiter recorded in sheep, cattle and goats. The thyroid gland is enlarged, there is a high neonatal mortality, a silky wool in sheep and a rough, sparse haircoat in goats. Called also inherited goiter.
goitrogen-induced goiter
there are a number of goitrogens in the environment of grazing animals. Their effect is almost entirely on the newborn. Common agents are low level intakes of cyanogenetic glycosides, e.g. in white clover, the glucosinolates in Brassica spp. plants, and mimosine in Leucaena leucocephala.
hyperplastic goiter
diffuse hyperplasia is the standard response to dietary iodine deficiency and to poisoning by plant goitrogens. It may also be caused by persistent exposure of the fetus to a high iodine intake of the dam. See also iodide goiter (below). Neonates are the usual subjects and the disease is manifested by clinical goiter, often sufficient to cause dystocia, and weak neonates with a high rate of stillbirths and deaths soon after birth.
inherited goiter
see dyshormonogenetic goiter (above).
iodide goiter
that occurring in reaction to iodides at high concentrations, due to inhibition of iodide organification.
nodular goiter
an endocrinologically inactive nodular enlargement of the thyroids in old dogs and horses. In old cats similar goiters sometimes develop functional adenomas.
References in periodicals archive ?
The final diagnosis of the case was that of a primary mediastinal ectopic goitre with vascular supply from the brachiocephalic trunk.
A closed vacuum drain is inserted selectively based on the size of the goitre and the extent of the dissection and is removed within 48 to 72 hours.
The concomitant goitre with an underlying tracheomalacia had predisposed her for the scenario, resulting in collapse of airways and respiratory embarrassment leading to cardiac arrest.
Another study was done in Asir region in 2001 on schoolchildren which revealed a high prevalence of goitre among the population living in high altitude areas.
Initial diagnosis was made on the basis of history, physical examination and ancillary investigations ( Thyroid function tests [ TFTs] and pre-operative indirect laryngoscopy [IDL] in all patients, and other tests in selected cases such as 99m Technetium thyroid scan for toxic goitres, fine needle aspiration cytology [FNAC] for solitary, dominant and cold nodules, X-ray thoracic inlet for retrosternal extension in huge goitres, serum thyroglobulin and anti-thyroid antibodies, etc where indicated.
Endemic goitre in the absence of iodine deficiency in schoolchildren of the Northern Cape Province of South Africa.
Despite being iodine replete, goitre continues to be prevalent in mild to moderate degree of endemicity in most states of India (4-8).
Unlike the preoperative visual impression, the goitre was larger than expected and there was still a huge oedema of the neck region.
There may be bradycardia, periorbital edema, thinning of the outer third of the eyebrows, hoarse voice or goitre.