goblet cell


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Related to goblet cell: goblet cell carcinoid

gob·let cell

an epithelial cell that becomes distended with a large accumulation of mucinogen-containing secretory granules at its apical end, giving it the appearance of a goblet.

goblet cell

n.
Any of the specialized epithelial cells found in the mucous membrane of the stomach, intestines, and respiratory passages that secrete mucus.
A caliceal mucin-secreting, located in the lateral wall of the intestinal crypts, and in columnar epithelium of the GI tract

gob·let cell

(gob'lĕt sel)
An epithelial cell that becomes distended with a large accumulation of mucous secretory granules at its apical end, giving it the appearance of a goblet.
Synonym(s): beaker cell.

goblet cell

or

chalice cell

a cell shaped something like a wineglass that is present in the columnar epithelium of the mammalian intestine and secretes MUCIN.
References in periodicals archive ?
Characterization of four main cell types in gastric cancer: foveolar, mucopeptic, intestinal columnar and goblet cells. A histopathologic, histochemical and ultrastructural study of "early" and "advanced" tumours.
Goblet cell carcinoid should always be considered as a differential diagnosis in patients with suspected appendicitis with or without a mass formation.
Allergic mediators such as histamine, leukotrienes, and prostaglandins directly stimulate secretory activity of conjunctival goblet cells, while inflammatory cytokines may regulate the secretion, proliferation, and apoptosis of the many cells involved.
The results of previous studies in our laboratory show that the OVA-mediated increases in inflammatory cells around bronchi, goblet cell hyperplasia, and total numbers and differential counts of inflammatory cells in BALF were significantly inhibited by sevoflurane [13].
The sections were stained with hematoxylin and eosin, periodic acid Schiff (PAS) reaction for a demonstration of goblet cells, and chloroacetate esterase reaction for a demonstration of neutrophil granulocytes.
Other common features of airway injury in asthma are remodelling of the airway structures, which includes epithelial damage, increased airway smooth muscle, mucous gland hypertrophy, and goblet cell hyperplasia [31-34].
The major findings of the present study are as follows: (1) normal organoids showed cystic structures and contained epithelial cells, goblet cells, and fibroblasts but not myofibroblasts (Figure 1), (2) tumor organoids showed robust expansion and replicated the epithelial structures compared with original tissues (Figure 2), (3) tumor organoids contained epithelial cells, goblet cells, myofibroblasts, and cancer stem cells (Figure 3), and (4) these tumor organoids were more resistant to 5-FU and Irinotecan compared with 2D cell cultured cells (Figure 4).
Group 1 (sham-control) rats exhibited goblet cell deformation, a reduction in goblet cell numbers, and mucus discharge from hypertrophic goblet cells (Figure 2).
Nadel, "Relationship of epidermal growth factor receptors to goblet cell production in human bronchi," American Journal of Respiratory and Critical Care Medicine, vol.
Research has found that patients with dry eye disease have a significant reduction in goblet cell density when compared with normal, healthy eyes.
Also, Mann- Whitney was used to evaluate the nonparametric data in small intestine tissue evaluating for presence (+) or absence (-) of necrosis, apoptotic changes and also goblet cell depletion.