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1. the science of maintaining a microbiologically controlled environment.
2. the science of raising laboratory animals whose microflora and microfauna are specifically known in their entirety.
n. (used with a sing. verb)
The study of organisms or environmental conditions that have been rendered free of bacteria or contaminants or into which a known microorganism or contaminant has been introduced for research purposes.
gnotobiotics(nō″tō-bī-ŏt′ĭks) [Gr. gnotos, known, + bios, life]
The study of animals that have been raised in germ-controlled or germ-free surroundings.
the science of rearing gnotobiotes. Also used in the more general sense of rearing specific pathogen free animals for use in a disease-free environment on commercial farms.