coli LpxB, which was generated by the mutation of a surface-exposed hydrophobic patch, showed that LpxB forms a glycosyltransferase
B (GT-B) dimer with a unique C-terminal swap wherein the last 87 residues of one subunit complete the fold of the opposite subunit (Figure 9) [62-64].
This issue was explained by modulation of von-Willebrand Factor (vWF) by A and B glycosyltransferase
The modification of ganglioside expression in oncogenesis is mainly associated with altered glycosyltransferase
and sialyltransferase activities .
It reported that deficiency of the [beta]1,4GalT1 glycosyltransferase
in genetic remodeling mouse could cause IgAN.
Wen et al., "Identification of the two glycosyltransferase
genes responsible for the difference between Escherichia coli O107 and O117 O-antigens," Glycobiology, vol.
NL119 is an ST1 strain one of the types hazardous to humans, but one that has lost the capsule because of a point mutation that occurred at nt 490 (T490C, Cysl64Arg) of a glycosyltransferase
gene (cps2F) (Table; Figure 1, panel A) (4).
The ABO gene encodes a glycosyltransferase
with three mainvariant alleles (A, B, and O) with different substrate specificities [Reid and Mohandas, 2004].
SOX9 transduction increases chondroitin sulfate synthesis in cultured human articular chondrocytes without altering glycosyltransferase
and sulfotransferase transcription.
Rational design of cyclodextrin glycosyltransferase
from Bacillus circulans strain 251 to increase alpha-cyclodextrin production.
Bellbrook added that the new Transcreener UDP TR-FRET Assay will better serve a growing need for robust, HTS-proven glycosyltransferase
assays for drug discovery.
These SNPs, rs6976 and rs11177, lie in the 3'UTR of glycosyltransferase
8 domain containing 1 (GLT8D1) and in the coding region of guanine nucleotide binding protein-like 3 (GNL3 or nucleostemin), respectively.
function in core 2-type protein O glycosylation.