Their product line includes a broad range of sphingolipids, glycolipids,
glycosphingolipids, fatty acids and esters, sterols, and vitamin E isomers (tocopherols and tocotrienols).
Generalized accumulation of neutral
glycosphingolipids with GM2 ganglioside accumulation in the brain.
The role of
glycosphingolipid biosynthesis-ganglioseries in CAD disease was also revealed by recent studies.
Takamori, "Significance of
glycosphingolipid fatty acid chain length on membrane microdomain-mediated signal transduction," FEBS Letters, vol.
Schmitz et al., "Tumor-specific Hsp70 plasma membrane localization is enabled by the
glycosphingolipid Gb3," PLoS One, vol.
The globoseries
glycosphingolipid SSEA-4 is a marker of bone marrow-derived clonal multipotent stromal cells in vitro and in vivo.
The basic principal of ERT involves the intravenous administration of fully functional enzyme that is taken up by the cells and then delivered to the lysosomes, where the delivered enzyme compensates for the deficient enzyme.In SRT, small molecule drugs are ingested orally, which inhibit the first step in
glycosphingolipid biosynthesis, aiming to reduce the rate of
glycosphingolipid biosynthesis resulting in reduction of the catabolic effects.
Neurological deficits and
glycosphingolipid accumulation in saposin B deficient mice.
Since the reaction proceeds under mild reaction conditions, this original accelerator, Sn[Cl.sub.2]-AgCl[O.sub.4], was utilized by many researchers in the synthesis of complex glycosides such as Avermectin, (18) Trimeric Lex, (19) Agelagalastatin, (20) [beta]-Mannoside, (21) and
glycosphingolipid KRN7000 (Fig.
The anti-asialo-GM1 mouse monoclonal antibody acts against the
glycosphingolipid asialo-GM1 antigen, which is expressed on murine NK cells [16].
As shown in Table 2 and Figure 1(a), the significant (P < 0.05) pathways corresponding to downregulated miRNAs were as follows: Fatty acid elongation, Arrhythmogenic right ventricular cardiomyopathy (ARVC), Other types of O-glycan biosynthesis, Thyroid hormone synthesis, Tyrosine metabolism, Mucin type O-glycan biosynthesis, Other glycan degradation,
Glycosphingolipid biosynthesis-lacto and neolacto series, Tryptophan metabolism, Gap junction, Proteoglycans in cancer, and signalling pathways regulating pluripotency of stem cells.
CA 19-9 is a
glycosphingolipid of the Lewis group that is well known as a tumor-associated antigen.
