The main components of these compounds are glycosides that consist of a glycon part and an aglycon part connected through a
glycosidic bond that can be created by a glycosylation reaction.
Background: Hyaluronidase is part of extracellular bacterial structure that degrade hyaluronic acid, hyaluronidases event by [BETA] elimination of the [BETA]-1,4
glycosidic bond in hyaluronic acid .
The cellulose is a glucose homopolymer with
glycosidic bond in the fourth position, through intra and intermolecular hydrogen bonds.
Finally, cellobiase acts by cleaving the [beta]-1,4
glycosidic bond of cellobiose and small oligosaccharide molecules with release of monomeric sugars (WOOD; McCARE, 1979; BHAT, 2000).
15) Enzymes involved in
glycosidic bond synthesis represent more than 1% of all open-reading-frame genes in M.
2] to form reactive oxygen species, and restricted oxidative cleavage of
glycosidic bond.
Beginning with
glycosidic bond formation, the contributors provide the most recent developments in stereoselectivity and therapeutic relevance for advanced biochemistry students, as well as research scientists in the field of biosynthesis, biopathways and vaccination studies.
Glycosyl hydrolases are a widespread group of enzymes that hydrolyze the
glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non carbohydrate moiety (Henrissat et al.
Whereas a
glycosidic bond made between [alpha] anomers of glucose is relatively easily hydrolyzed by mammalian enzymes, a
glycosidic bond made between [beta] anomers of glucose can only be hydrolyzed by the enzymes made by microbes such as those inhabiting the digestive tract of livestock.
These mutants of retaining glycosidases have had the catalytic glutamate nucleophile replaced with alanine, glycine, or serine, preventing the usual double displacement mechanism for
glycosidic bond cleavage.
1] (cellulose beta
glycosidic bond stretching vibration).
Hyaluronidase SD (from Streptococcus dysgalactiae) is an eliminase, which catalyzes the eliminating cleavage of the [beta]1-3
glycosidic bond between N-acetylglucosamine and glucuronic acid residues of HA.
