Harmatz, the trial will investigate leukocyte
glycosaminoglycan (leukoGAGs) levels in three children and skin
glycosaminoglycan (skinGAGs) levels in three adults with MPS VI before and post enzyme replacement therapy (ERT), and in six age-matched control subjects not affected by MPS VI.
Disaccharide analysis of skin
glycosaminoglycans in atrophoderma of Pasini and Pierini.
(NASDAQ : SGMO) reported 16 week reductions in urinary
glycosaminoglycans, a key biomarker of Mucopolysaccharidosis Type II (MPS II) disease pathophysiology, in Cohort 2 of the Phase 1/2 CHAMPIONS Study evaluating SB-913.
Delayed gadolinium-enhanced magnetic resonance imaging of cartilage (dGEMRIC) enables noninvasive assessment of
glycosaminoglycan (GAG) content in cartilage.
Formato et al., "Urinary
glycosaminoglycans in patients with systemic lupus erythematosus," Clinical and Experimental Rheumatology, vol.
Glucosamine is a component of
glycosaminoglycans, which is derived from shellfish.
The SimGlycan master database is updated with curated (a) N-glycans derived from Monoclonal antibody (mAb), Bovine Fetuin, Chinese Hamster Ovary (CHO), (b)
glycosaminoglycans derived from Low Molecular Weight Heparin (LMWH), and (c) polysaccharides derived from plants.
Dynamic ECMs form the microenvironment around cells and are composed of collagens, glycoproteins,
glycosaminoglycans (GAGs), and proteoglycans (PGs).
Lysosomal storage disorders (LSDs) (4) are genetic diseases caused by deficiencies of activities of enzymes that degrade substrates including glycolipids,
glycosaminoglycans, and proteins (1).
Proteoglycans are a subset of complex ECM proteins with attached
glycosaminoglycans and have unique properties.
Purpose:
Glycosaminoglycans (GAGs) and proteoglycans (PG) in addition to collagen are the main components of extracellular matrix (ECM).
Changes in
glycosaminoglycans and related proteoglycans in intrinsically aged human skin in vivo.