glycophorin


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glycophorin

 [gli″ko-for´in]
any of several related proteins that can project through the thickness of the cell membrane of erythrocytes; they attach to oligosaccharides at the outer cell membrane surface and to contractile proteins (spectrin and actin) at the cytoplasmic surface.

glycophorin

a glycopolypeptide found in human erythrocytes.
References in periodicals archive ?
The Mia is the product of a hybrid gene, probably a mutation or crossover events of glycophorin A and glycophorin B responsible for the unique glycophorin hybrid peptide, Gp.Mur phenotype.
(1,3-9,12) Eosinophilic globules, when present, stain with Masson trichrome and ai-antitrypsin and lightly with PAS (Figure 3), but not with hemoglobin or glycophorin C stains.
Wherever indicated the primary panel was extended up to (secondary panel) antibodies against cytoplasmic (cyt) CD3, CD4, CD8, myeloperoxidase (MPO), terminal deoxynucleotidyl transferase (TdT), CD79, CD41, CD61 and glycophorin. All these monoclonal antibodies were labeled with either of fluorescein isothiocyanate (FITC), phycoerythin (PE) or peridine chlorophyll protein (PerCP).
Lu et al., "Early development of definitive erythroblasts from human pluripotent stem cells defined by expression of glycophorin A/CD235a, CD34, and CD36," Stem Cell Reports, vol.
EV origin Surface markers Endothelium [CD31.sup.+]/[CD41.sup.-]([PECAM.sup.+]/[ITGA2B.sup.-]) [CD31.sup.+]/[CD42.sup.-] ([PECAM.sup.+]/[GPIb.sup.-]) CD31 (PECAM (platelet cell adhesion molecule)) CD144 (VE cadherin (vascular endothelial cadherin)) CD146 (MCAM (melanoma cell adhesion molecule)) CD105 (endoglin) CD106 (VCAM (vascular cell adhesion molecule)) CD62E (E-selectin (endothelial-selectin)) Platelet CD41 (ITGA2B (integrin alpha 2b)) CD42 (GPIb (glycoprotein Ib)) CD31 (PECAM (platelet cell adhesion molecule)) Leukocyte CD45 (PTPRC (protein tyrosine phosphate receptor type C)) CD11b (ITGAM (integrin alpha M)) CD14 (coreceptor of lipopolysaccharide) CD16 (on surface of neutrophils, monocytes, and macrophages) CD62L (L-selectin (leukocyte selectin)) Red blood cell CD235 (glycophorin A)
Desialylation of glycophorin (127) is responsible for the clearance of aged erythrocytes (128).
A notable example is the identification of glycophorin B as the erythrocyte receptor for P falciparum protein EBL-1 through examination of highly polymorphic genes in populations from malaria-endemic regions [50].
In COPD patients, RBC were shown to alter morphologically, like cytoskeleton changes, ultrastructural modifications, and reductions of glycophorin A, band 3, and RBC thiols [7, 18, 19].
Mutations in genes coding for protein 4.1, alpha spectrin, beta spectrin, band 3, and Glycophorin C have all been implicated in hereditary elliptocytosis [4, 5].
Furthermore, immunohistochemical analysis of surgical sample was performed by using glycophorin A (DAKO, clone: JC159, 1:400) for erythroblasts, CD41 (Calbiochem, clone: 283.16B7, 1:2000) for megakaryocytes, and MPO (DAKO, rabbit polyclonal, 1: 500) for granulocytes (Figure 4).
Tenders are invited for Supply of IHC Antibodies, Chromogranin 6-7ml vial, Synaptophysin 6-7ml vial, P63 6-7ml vial, Thyroglobulin 6-7ml vial, Glycophorin A 3-4ml vial, EBV-LMP-1 3-4ml vial etc.for the department of pahtology.