glycome


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Related to glycome: Glycomics, glycan, Metabolome

glycome

(glī′kōm′)
n.
The complete set of carbohydrates that are metabolized by an organism.

glycome

(glī′kōm″) [ glyc- + -ome]
The complete set of carbohydrates within an organism.
References in periodicals archive ?
Further experiments designed to elucidate the HDL glycome, the biology of HDL-glycosylated proteins, and their effects on HDL metabolism, size, and function will be of great interest and help determine potential mechanisms involved in the current observations.
Once passing the debranching enzyme, the glycome is picked up by hexokinase and phosphorylated by ATP to become glucose-6-phosphate.
Glycomics is the study of glycome structures (sugars, modified sugars and saccharides) in molecules and organisms, a tangled web of carbohydrates, proteins and lipids that modulate cellular function and play a primary role in the development of cancer, bacterial and viral diseases, and glycan-specific hereditary diseases.
Defining a glycome as the entire complement of glycan structures within a cell, molecular biologists from Australia, Europe, and North America provide an overview of bacterial glycans, which differ in some important ways from eukaryote glycans.
Salicinium, a natural plant extract, is a complexed glycome (sugar) molecule that enters into a metabolic reaction, shutting down the ability of the cancer cell to hide from the immune system.
Among specific topics are mechanisms of membrane curvature sensing, the assembly of bacterial inner membrane proteins, applying mass spectrometry to lipids and membranes, the biochemistry of mobile zinc and nitric oxide revealed by fluorescent sensors, DNA replicases from a bacterial perspectives, the structure of the nuclear pore complex, glycan microarrays for decoding the glycome, and mitochondrial tRNA import and its consequences for mitochondrial translation.
Salicinium, a natural plant extract, is a glycome (complex sugar molecule) that enters into a metabolic reaction which shuts down the ability of the cancer cell to hide from the immune system.
Correspondingly, metabolic dysfunctions and disease states may be reflected in the appearance of abnormal glycans or altered quantitative proportions within the glycome.
Glycomics studies at the whole-tissue level provide a general overview on the glycome, the total glycosylation pattern of glycoproteins, lipids, or other types of biomolecules.
Glycomics research is important for comprehensive study of glycomes to understand the cellular signaling pathways, cell functions, genetic structure, and physiological and pathological aspects.
in support of these aims, this foa is intended to develop new approaches (catalytic methods, chemical/chemo-enzymatic methods, and technologies) to facilitate the rapid, robust, and affordable synthesis, and/or functionalization of bio-medically relevant glycans and glyco-conjugates representing 1) mammalian glycomes and 2) microbial glycans.