glycineamide ribonucleotide

(redirected from glycinamide ribonucleotide)

gly·cine·a·mide ri·bo·nu·cle·o·tide

, glycinamide ribonucleotide (glī'sin-ă-mīd rī'bō-nū'klē-ō-tīd, glī-sin'a-mīd rī'bō-nū'klē-ō-tīd),
An intermediate in purine biosynthesis, in which the amide nitrogen of glycineamide is linked to the C-1 of a ribosyl moiety.
References in periodicals archive ?
The cDNA inserts that were used as probes were those homologous to rRNA, and to mRNAs encoding acetyl CoA carboxylase (ACC), lipoxygenase (LO), glucosyltransferase, inorganic phosphate translocator, nitrate reductase, and glycinamide ribonucleotide (GAR) synthetase/GAR transformylase.
De novo purine nucleotide synthesis: cloning of human and avian cDNAs encoding the trifunctional glycinamide ribonucleotide synthetase-aminoimidazole ribonucleotide synthetase-glycinamide ribonucleotide transformylase by functional complementation in E.
One potential drawback of this approach is that it does not separate and quantify long-chain MTXPGs, which are known to have greater effects on the targets of MTX, such as glycinamide ribonucleotide transformylase and 5-aminoimidazole-4-carboxamide-ribonucleotide transformylase (30).