glycerophosphocholine


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glyc·er·o·phos·pho·cho·line

(glis'ĕr-ō-fos'fō-kō'lēn),
A component of phosphatidylcholines (lecithins), in which the two OH's of glycerophosphocholine are esterified with fatty acids.

glycerophosphocholine

,

GPC

A metabolite of lecithin. It is a phospholipid precursor.
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References in periodicals archive ?
Fuchs, "Hypochlorous acid-mediated generation of glycerophosphocholine from unsaturated plasmalogen glycerophosphocholine lipids," The Journal of Lipid Research, vol.
1: Lipids C[H.sub.3], branched chain amino acids; 2: Lipids C[H.sub.2]; 3: Lactate (Lac); 4: Alanine (Ala); 5: Glutamine (Gln), Glutamic acid (Glu); 6: Creatine (Cr); 7: Choline (Cho), Phosphocholine (PC); 8: Glycerophosphocholine (GPC); 9: Taurine (Tau); 10: Glycine (Gly); 11: [beta]-Glucose ([beta]-Glc); 12: Uridine 5'-diphospho-N- acetylglucosamine or Uridine 5'-diphospho-N-acetylgalactosamine (UDP); 13: Nicotinamide adenine dinucleotide 2'- diphosphate ([NADP.sup.+]).
PNPLA6 encodes for neuropathy target esterase (NTE), a lysophospholipase that maintains intracellular phospholipid homeostasis by converting lysophosphatidylcholine to glycerophosphocholine (42).
Galantamine is often used in combination with other supplements, such as choline (often in the form of glycerophosphocholine), a precursor to the important acetylcholine neurotransmitter.
Spence, "Phosphatidylcholine metabolism in cultured cells: catabolism via glycerophosphocholine," Biochimica et Biophysica Acta, vol.
(18,21) The Cho peak in the [1.sup]H-MRS of the brain is thought to be composed of cytosolic glycerophosphocholine and phosphocholine, which are the products of membrane phosphatidylcholine breakdown, as well as precursors of Cho and acetylcholine synthesis.
They also found no changes after the night of total sleep deprivation, but the morning after one recovery sleep night, total NTP, [gamma]-NTP, [beta]-NTP, and glycerophosphocholine (GPC; a measure of phospholipid degradation) were increased [18].
The influence of inflammation of the human male genital tract on secretion of the seminal markers alpha-glucosidase, glycerophosphocholine, carnitine, fructose and citric acid.
The three commercially available phospholipids are phosphatidylserine (PS), phosphatidylcholine (PC) and glycerophosphocholine (GPC).Of these, PS and GPC have shown the most promise for cognition in research.
The total Cho peak (phosphocholine, free Cho, and glycerophosphocholine) is a marker of cell membrane integrity and viability.
Researchers at the University of Palermo in Italy tested the molecule, called glycerophosphocholine (GPC), for its effect on neurological functioning in 2,044 stroke victims.
This group of molecules consists of several breakdown products of membrane phos-pholipid components, such as glycerophosphocholine, glycerophophoethanolamine, and glycerophosphoinositol.