In this study, various zinc glutarate derivatives were newly prepared by the reaction of zinc oxide with ten different glutaric acid derivatives.
Ten different glutaric acid derivatives were purchased from Aldrich Chemical Company: glutaric acid (GA), 2,2-dimethylglutaric acid (2,2-DMGA), 3,3-dimethylglutaric acid (3,3-DMGA), 2-methylglutaric acid (2-MGA), 3-methylglutaric acid (3-MGA), 3-phenylglutaric acid (3-PhGA), 2-ketoglutaric acid (2-KetoGA), 3-ketoglutaric acid (3-KetoGA).
Here, the amount of reacted ZnO was estimated by measuring the amount of unreacted glutaric acid obtained after removal of the used toluene and acetone from the filtrate.
Zinc oxide is insoluble in solvents, such as benzene, ethanol and toluene, so that zinc dicarboxylate catalysts have been prepared via its slurried reactions with glutaric acid derivatives and diglycolic acid.
The results indicate that all the side group substituents considered reduce the reactivity of glutaric acid to zinc oxide, giving relatively low reaction yields.
Various zinc dicarboxylate catalysts were synthesized from the reaction of zinc oxide with ten different glutaric acid derivatives and diglycolic acid.
The concentrations obtained were as follows: methylmalonic acid, 0.011 mol/L (3089 mmol/mol creatinine); pyroglutamic acid, 0.017 mol/L (25 682 mmol/mol creatinine); and glutaric acid
, 0.055 mol/L (82 879 mmol/ mol creatinine).