glu·tam·i·nyl (Gln, Glx, Q),

The acyl radical of glutamine.
Farlex Partner Medical Dictionary © Farlex 2012


(Gln) (glū-tam'i-nil)
The acyl radical of glutamine.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Current projects are focusing on the two isoenzymes of Glutaminyl cyclase, QPCT and QPCTL.
Cerebrospinal fluid glutaminyl cyclase (QC) activity has been found to correlate with Alzheimer's disease biomarkers and inflammation molecules in AD patients.
Deamidation of glutaminyl and asparaginyl residues in peptides and proteins.
Fremont, CA, May 29, 2014 --( AnaSpec is pleased to announce the release of the first commercially available 96-well format, fluorimetric assay for measuring Glutaminyl Cyclase (QC) activity - the SensoLyte[R] Green Glutaminyl Cyclase Activity Assay Kit.
In this context, disease-specific autoantibody profiles [20], increased glutaminyl cyclase expression [21], and angiopoietin-1 levels [22]have also been described in human sera.
Probiodrug AG (Halle Saale, Germany) has patented physiological substrates of mammalian glutaminyl cyclase (QC, EC, new effectors of QC, methods for screeing for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity.
As you may know, transglutaminase is a transferase that forms isopeptide bonds between lysyl and glutaminyl residues.
Glutaminyl cyclase cyclizes N-terminal glutamine to pyroglutamic acid in such peptides as TRH.
The exception is the C-terminal glutaminyl amide, and so the specific modulatory action of YFAFPRQamide on the clam gill cilia can probably be attributed to this residue.
4 January 2012 - Probiodrug AG, a German biopharmaceutical company, said on Wednesday that it had raised EUR15m (USD19.6m) in fresh funding for the development of its glutaminyl cyclase (QC) inhibitor program.
12:15 DRUGS BOUND TO THE ENZYME HUMAN GLUTAMINYL CYCLASE **, Breanna Spires and Robert Zurales, Middle Georgia College, Cochran, GA 31014.