Normal Control Ccl4 Control LIV-52 AEPF-250 AEPF-500 SGOT 135 314.4 141.6 212.8 172.8 SGPT 60.2 256.4 98 181.2 136 ALP 213.2 430 246.8 310.4 266.8 CHOLESTEROL 120.4 185.8 127.4 161.6 147.2 Figure 1: Effect of Phyllanthus fraternus on serum glutamic oxaloacetic transaminase, serum glutamic pyruvic transaminase
, alkaline phosphatase, and cholesterol in [CCl.sub.4]-induced hepatotoxicity in Wistar rats Note: Table made from bar graph.
GOT: glutamic oxaloacetic transaminase; GPT: glutamic pyruvic transaminase
; BUN: blood urea nitrogen; Cre: creatinine.
Before starting DCP therapy, patients were tested for hemoglobin, erythrocyte sedimentation rate, total and differential leucocyte count, platelets count, serum creatinine, serum glutamic oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase
(SGPT) and blood sugar levels.
Liver function test revealed mildly elevated transaminase levels (Serum glutamic oxalate transaminase/serum glutamic pyruvic transaminase
: 68/64 U/L) and elevated serum alkaline phosphatase (206 U/L), bilirubin was 0.6 mg%.
They were screened by way of a medical history, blood chemistry (complete blood cell count, glucose, lipid profile, creatinine, serum glutamic pyruvic transaminase
(SGPT)) electrocardiogram (ECG), anthropometry, and health questionnaires.
Abbreviations Full Form 1 Hb Haemoglobin 2 PCV Packed cell volume 3 HCT Haematocrit 4 TLC Total leukocyte count 5 DLC Differential leukocyte count 6 PT Prothrombin time 7 aPTT Activated partial thromboplastin time 8 SGOT Serum glutamic oxaloacetic transaminase 9 AST Aspartate transaminase 10 SGPT Serum glutamic pyruvic transaminase
11 ALT Alanine transaminase 12 KFT Kidney function test 13 LFT Liver function test 14 ECG Electrocardiogram 15 R/M Routine and microscopy 16 C/S Culture and sensitivity 17 CXR Chest x-ray 18 USG Ultrasonography ACKNOWLEDGEMENT
The levels of glutamic oxaloacetic transaminase (GOT), glutamic pyruvic transaminase
(GPT), and total cholesterol were measured according to the colorimetric method using biochemical analyzer (Hitachi modular system, Hitachi Ltd., Tokyo, Japan).
Attributes contain information about glutamic oxaloacetic transaminase, glutamic pyruvic transaminase
, lactate dehydrogenase, gamma-glutamyl transpeptidase, blood urea nitrogen, mean corpuscular volume of red blood cells, mean corpuscular hemoglobin, total bilirubin, and creatinine.
On applying the unpaired t-test, we found that adverse fetal outcomes were significantly associated with rising serum bilirubin levels of more than 11 mg/dL, serum glutamic oxaloacetic transaminase (SGOT) and serum glutamic pyruvic transaminase
(SGPT) of more than 1000 IU/L, and a platelet count of less than 85.000 cells/[mm.sup.3], and this difference was statistically significant.
Initial laboratory tests showed mild leukocytosis (WBC: 10000/[micro]L, segment: 84.1%), Hb 14.4 g/dL, platelet count 163000/[micro]L, glutamic pyruvic transaminase
(GPT) 22IU/L, creatinine 1.0 mg/dL, troponin I 0.06 ng/mL, and creatinine kinase MB 0.8/ng/Ml.
In terms of adverse effects of ATT (Table-3), 26(54.16%) clinicians reported raised serum glutamic pyruvic transaminase
(SGPT) as the commonest adverse effect.