glutamate dehydrogenases

glu·ta·mate de·hy·dro·gen·as·es

enzymes that catalyze the reaction of l-glutamate, H2O, and NAD+ (or NADP+ in some cases) producing α-ketoglutarate (2-oxoglutarate), ammonia, and NADH; in mammals, this is the prime contributor to oxidative deamination.
References in periodicals archive ?
[27.] Turner, AC, Lushbaugh, WB and Hutchison, WF, "Dirofilaria immitis: comparison of cytosolic and mitochondrial glutamate dehydrogenases", Experimental Parasitology 1986; 61: 176-183.
Estimates of [K.sub.m] and [V.sub.max] obtained with the glutamate dehydrogenases (GDHs) of Trichomonas vaginalis [26], Dirofilaria immitis [27] and Teladorsagia circumcincta [25, 28], and the glutamate synthase (GS) of T.
[26.] Turner, AC and Lushbaugh, WB, "Trichomonas vaginalis: characterization of its glutamate dehydrogenase", Experimental Parasitology 1988; 67: 47-53.
[31.] Skuce, PJ, Stewart, EM, Smith, WD and Knox, DP, "Cloning and characterization of glutamate dehydrogenase (GDH) from the gut of Haemonchus contortus", Parasitology 1999; 118: 297-304.
Glutamate dehydrogenase." Experimental Parasitology 1973; 34: 100-110.
(iii) related enzymes may exhibit SI in some conditions, as is the case glutamate dehydrogenase [4].
[4.] Umair, S, Knight, JS, Patchett, ML, Bland, RJ and Simpson, HV, "Molecular and biochemical characterisation of a Teladorsagia circumcincta glutamate dehydrogenase", Experimental Parasitology 2011; 129: 240-246.
[13.] Rife, JE and Cleland, WW, "Kinetic mechanism of glutamate dehydrogenase", Biochemistry 1980; 19: 2321-2328.
[14.] Muhamad, N, Brown, S, Pedley, KC and Simpson, HV, "Kinetics of glutamate dehydrogenase from L3 Ostertagia circumcincta", New Zealand Journal of Zoology 2004; 31: 97.

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