glucuronide


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glucuronide

 [gloo-ku´ron-īd]
any glycosidic compound of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols, and carboxylic acids.

glu·cu·ro·nide

(glū-kū'rōn-īd),
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (for example, steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Synonym(s): glucuronoside

glucuronide

/glu·cu·ron·ide/ (gloo-ku´ron-īd) any glycosidic compound of glucuronic acid; they are common soluble conjugates formed as a step in the metabolism and excretion of many toxins and drugs, such as phenols and alcohols.

glu·cu·ro·nide

(glū-kyūr'ō-nīd)
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (e.g., steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.

glucuronide

any glycosidic conjugate of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols and carboxylic acids.
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References in periodicals archive ?
Incomplete recovery of prescription opioids in urine using enzymatic hydrolysis of glucuronide metabolites.
Approaches to prescription opioid abuse testing: urgency drives new techniques
Bisphenol A glucuronide, a major metabolite in rat bile after liver perfusion.
In vitro effects of bisphenol A [beta]-D-glucuronide (BPA-G) on adipogenesis in human and murine preadipocytes
Moreover, the metabolite hydroxyemodin glucuronide was first reported in this article.
Structural Elucidation of in Vitro and in Vivo Metabolites of Emodin in Rats by LC -ESI-MS/MS
This enabled identification of un-metabolised urinary flavonolignans and urinary phase II metabolites, such as glucuronides, sulphate-glucuronides and diglucuronides.
Absorption and metabolism of milk thistle flavonolignans
Paracetamol poisoning (2,4) The majority of paracetamol (90 per cent) is normally metabolised in the liver, via phase II conjugation with glucuronide or sulphate molecules.
Metabolism and excretion: eliminating drugs from the body
Comparison of ethyl glucuronide and fatty acid ethyl ester concentrations in hair of alcoholics, social drinkers and teetotallers.
Carbohydrate deficient transferrin and alcoholism
glucuronide (I-G) and sulfate (I-S) in urine and bile were estimated across various species.
Metabolism of halogenated hydroxyquinolines
In urine and feces, acyl glucuronide metabolites of febuxostat (~35% of the dose), and oxidative metabolites (~10% of the dose) and a secondary metabolite form, (~14% of the dose) appeared to be the major metabolites of febuxostat in vivo.
Febuxostat--a new treatment for hyperuricaemia in gout --a review article
Defendants were leading proponents of ethyl glucuronide (EIG) testing.
RN in rehab program challenged flawed alcohol tests
Urinary tract infection: A risk factor for false-negative urinary ethyl glucuronide but not ethyl sulfate in the detection of recent alcohol consumption.
Focus on: biomarkers of fetal alcohol exposure and fetal alcohol effects
The NailStat and HairStat EtG tests measure ethyl glucuronide (EtG) - a minor product of alcohol metabolism.
Nails, hair indicate booze intake over last 90 days
The tester reported that ethyl glucuronide (EtG) had been detected and that the results were consistent with alcohol use in the last month before testing.
Hair testing for alcohol in care proceedings

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