glucuronide


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glucuronide

 [gloo-ku´ron-īd]
any glycosidic compound of glucuronic acid; glucuronides, which are generally inactive, constitute the major proportion of the metabolites of many phenols, alcohols, and carboxylic acids.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

glu·cu·ro·nide

(glū-kū'rōn-īd),
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (for example, steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Synonym(s): glucuronoside
Farlex Partner Medical Dictionary © Farlex 2012

glu·cu·ro·nide

(glū-kyūr'ō-nīd)
A glycoside of glucuronic acid; many foreign chemicals, as well as catabolic products of normal body constituents (e.g., steroid hormones), are commonly excreted in the urine as d-glucuronides, the conjugation taking place in the liver.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
In this study, we compared the FF compounds found in the older group and younger group, and only the samples from the older group contained nicotine glucuronide, which, when present in the FF during oocyte development, has an adverse effect on the reproductive system, decreasing female reproductive function.
Probenecid, uricosuric drug in the treatment of gout, interferes with renal excretion of steroid glucuronides. Inhibitors of 5[alpha] reductase, the class of pharmacological agents in the treatment of benign prostatic hyperplasia, alter metabolism of anabolic steroids reducing excretion of dihydrotestosterone and androsterone.
Urinary and circulating levels of BA-Gs detected in the present study are similar to previous findings in terms of both glucuronide concentrations and species distribution [13, 14, 16].
Increasing the number of glucuronides at position 7 of the A ring (compound 6) in the skeleton of compound 10 increased its inhibitory activities on protein glycation.
Chowrimootoo et al., "Resveratrol is absorbed in the small intestine as resveratrol glucuronide," Biochemical and Biophysical Research Communications, vol.
Ex vivo studies, that use organ perfusion techniques, and in vivo studies using rats have shown that resveratrol can be passively absorbed and conjugated with glucuronic acid or sulfate to form resveratrol glucuronide or resveratrol sulfate [27, 28].
Mechanism of this syndrome is metabolism of tramadol in liver by hydroxylation and conjugation with glucuronide which leads to metabolism of SSRI via competitive inhibition.
Free curcumin, rather than its conjugated metabolites (such as glucuronide), appears to be required in order for this important compound to gain entry into tissues, including the brain.
Listeria Chromogenic Agar for the isolation of Listeria monocytogenes and Tryptone Bile Glucuronide Agar for the isolation of Escherichia coli will be closely followed by CSIM for the isolation of Cronobacter sakazakii from milk and milk products and chromogenic ABC medium for the isolation of Salmonellae.
Listeria Chromogenic Agar for the isolation of Listeria monocytogenes and Tryptone Bile Glucuronide Agar for the isolation of E.coli will be closely followed by CSIM for the isolation of Cronobacter sakazakii from milk and milk products and chromogenic ABC medium for the isolation of salmonellae.