glucosidase inhibitors

glu·co·si·dase in·hib·i·tors

agents (for example, acarbose) that reduce gastrointestinal absorption of carbohydrates. This group of drugs has been known popularly as "starch blockers." They lower plasma glucose levels and tend to cause weight loss. A limiting side-effect is flatulence.

glu·co·si·dase in·hib·i·tors

(glū-kō'sid'ās in-hib'i-tŏrz)
Agents such as acarbose that reduce gastrointestinal absorption of carbohydrates. This group of drugs, known popularly as "starch blockers," lowers plasma glucose levels and tend to cause weight loss. Flatulence is a limiting side-effect.

glucosidase inhibitors

Drugs, such as acarbose (Glucobay), that interfere with the absorption of carbohydrates and are used as aids to weight loss. Acarbose is used to treat Type 2 diabetes that is inadequately controlled by diet and oral hypoglycaemics.

glu·co·si·dase in·hib·i·tors

(glū-kō'sid'ās in-hib'i-tŏrz)
Agents that reduce gastrointestinal absorption of carbohydrates; known popularly as "starch blockers." They lower plasma glucose levels and tend to cause weight loss but cause flatulence.
References in periodicals archive ?
Comparisons of the efficacy of alpha glucosidase inhibitors on type 2 diabetes patients between Asian and Caucasian.
The main concepts searched in English were sulfonylurea (SU); alpha glucosidase inhibitors (AGI); metformin (MET); thiazolidinediones (TZD); dipeptidyl peptidase-4 inhibitors (DPP-4i); sodium-glucose cotransporter 2 inhibitors (SGLT2i); glucagon-like peptide-1 receptor agonist (GLP-1RA); type 2 diabetes (T2DM); placebo controlled; and randomized controlled trials.
Alpha glucosidase inhibitors. J Pak Med Assoc 2014; 64(4): 474-6.
Alpha glucosidase inhibitors are suggested to be valuable aids in the treatment of diabetes.
The multiple functions of glucosidase inhibitors in the organism comprise the treatment of diabetes mellitus [10-13] and other diseases such as obesity, HIV infections, and tumors [14-23], which define these agents as potentially beneficial tools in prevention and treatment of such disorders.
Osajima, "Inhibitory effect of [alpha]- glucosidase inhibitors varies according to its origin," Journal of Agricultural and Food Chemistry, vol.
Alpha glucosidase inhibitors inhibit an enzyme found in the brush boarder of the small intestine, which is responsible for the breakdown of complex carbohydrates.
The most cost-effective drug is metformin following by economical sulphonylureas and their combination in more severe diabetic patients glucosidase inhibitors have a limited use as an adjunct drug.
Therefore, safer natural amylase and glucosidase inhibitors have been reported from plant sources [14-16].
Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors. Curr Diabetes Rev.
A total of 108 patients were on regimen A that included pioglitazone and subcutaneous human mixture insulin, 117 on B with pioglitazone and sulfonylurea, 87 on C with pioglitazone and metformin, 39 on D with pioglitazone and alpha glucosidase inhibitors; and 28 on E including pioglitazone monotherapy.
Among antidiabetic drugs sulfonylurea (65%) and biguanides (65%) were most frequently prescribed followed by thiazolidinediones (23%) and alpha glucosidase inhibitors (3%).