glucose-6-phosphate


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glu·cose-6-phos·phate

(glū'kōs fos'fāt)
An ester of glucose with phosphoric acid; made in the course of glucose metabolism by mammalian and other cells; a normal constituent of resting muscle.
References in periodicals archive ?
Case report: Acute Hepatitis E Infection with Co-Existent Glucose-6-Phosphate Dehydrogenase Deficiency.
Measurement Patient value Direct Coombs test Negative Total bilirubin 4.1 mg/dL (RI, <20 mg/dL) Conjugated bilirubin 0.4 mg/dL (RI, <0.4 mg/dL) G6PDH first sample ND mU/[10.sup.9] erythrocytes G6PDH second sample 2 mU/[10.sup.9] erythrocytes (RI, 138-171 (at age 10 d) mU/[10.sup.9] erythrocytes) RI, reference interval; G6PDH, glucose-6-phosphate dehydrogenase (Ref.
Beutler, "Glucose-6-phosphate dehydrogenase deficiency: a historical perspective," Blood, vol.
Rutigliano et al., "Metabolomic profile of glycolysis and the pentose phosphate pathway identifies the central role of glucose-6-phosphate dehydrogenase in clear cell-renal cell carcinoma," Oncotarget, vol.
Effect of experimental diabetes on the activities of hexokinase, glucose-6-phosphate dehydrogenase and catecholamines in rat erythrocytes of different ages.
Hexokinase (HK) activity was determined using a commercial kit (Jiancheng Bioengineering Institute, Nanjing, China) based on the coupled reactions of hexokinase with glucose-6-phosphate dehydrogenase which resulted in the formation of reduced form of nicotinamide-adenine dinucleotide (NADH).
G-6- P, glucose-6-phosphate; Ala, alanine; Trp, tryptophan; Ser, serine; Ile, isoleucine; Leu, leucine; Val, valine; His, histidine; Arg, arginine; Pro, proline; Glu, glutamic acid; Gln, glutamine; Lys, lysine; Met, methionine; Thr, threonine; Asp, aspartic acid; Asn, asparagine; Phe, phenylalanine; Tyr, tyrosine; and Gly, glycine.
We present a case of hemolysis in a glucose-6-phosphate dehydrogenase- (G6PD-) deficient patient receiving vitamin C infusions for his rheumatoid arthritis.
Tang, "Human glucose-6-phosphate dehydrogenase (G6PD) gene transforms NIH 3T3 cells and induces tumors in nude mice," International Journal of Cancer, vol.
Briefly, 5 x [10.sup.5] cells were cultured and after 96 h medium was collected and incubated for 30 minutes with glucose assay buffer (1.5 mM NAD, 1 mM ATP, 1 U/ml hexokinase and 1 U/ml glucose-6-phosphate dehydrogenase).
Another key enzyme, glucose-6-phosphate dehydrogenase (G6PdH), acts on the alternative pentose monophosphate pathway and is responsible for maintaining appropriate levels of NADPH in the cells (ASAI et al., 2011).

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