The comparisons of the L-dopa, clonidine and glucagon test results with the ITT response were not statically significant (Table 3).
The sensitivity and the specificity of the glucagon test were 100%.
showed that glucagon test had 88% sensitivity and 97% specificity in adults with GHD, when cut-off point was taken as 3 ng/mL.
In conclusion, glucagon, L-dopa and ITT have high negative predictive values, therefore, these tests, especially the glucagon test, should be firstly used in the evaluation of adolescent GHD patients.
Therefore, we investigated sensitivity, specificity, positive and negative predictivities of insulin-induced hypoglycemi-a, clonidine, L-dopa and glucagon tests in subjects with severe short stature.
Clonidine, L-dopa and glucagon tests were applied to 21, 32 and 12 patients, respectively.