glomerulosclerosis


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Related to glomerulosclerosis: focal segmental glomerulosclerosis

glomerulosclerosis

 [glo-mer″u-lo-sklĕ-ro´sis]
diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.
focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.

glo·mer·u·lo·scle·ro·sis

(glō-mer'yū-lō-sklē-rō'sis),
Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes.
[glomerulus + G. sklērōsis, hardness]

glomerulosclerosis

/glo·mer·u·lo·scle·ro·sis/ (glo-mer″u-lo-sklĕ-ro´sis) fibrosis and scarring resulting in senescence of the renal glomeruli.
diabetic glomerulosclerosis  intercapillary g.
focal segmental glomerulosclerosis  a syndrome of focal sclerosing lesions of the renal glomeruli with proteinuria, hematuria, hypertension, and nephrosis, with variable progression to end-stage renal disease.
intercapillary glomerulosclerosis  a degenerative complication of diabetes, manifested as albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy.

glomerulosclerosis

[-sklərō′sis]
Etymology: L, glomerulus, small ball; Gk, sklerosis, a hardening, osis, condition
a severe kidney disease in which glomerular function of blood filtration is lost as fibrous scar tissue replaces the glomeruli. The disease commonly follows an infection or arteriosclerosis.
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Glomerulosclerosis

glomerulosclerosis

Nephrology A degenerative lesion of the renal glomeruli caused by ASHD or DM. See Kimmelsteil-Wilson disease.

glo·mer·u·lo·scle·ro·sis

(glō-mer'yū-lō-skler-ō'sis)
Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes mellitus.
[glomerulus + G. sklērōsis, hardness]

glomerulosclerosis

A kidney disease in which many glomeruli (see GLOMERULUS), previously damaged by inadequate blood supply or GLOMERULONEPHRITIS, become replaced by a non-functioning glassy (hyaline) material. It sometimes occurs without prior damage. The effects resemble those of the NEPHROTIC SYNDROME and kidney function gradually deteriorates. Kidney failure is a common outcome.

glomerulosclerosis

renal glomerulus degeneration and fibrosis; associated with arteriosclerosis and diabetes

glomerulosclerosis

progressive hyalinization such that glomeruli become shrunken, eosinophilic and hypocellular masses.

intercapillary glomerulosclerosis
References in periodicals archive ?
Increasing incidence of focal segmental glomerulosclerosis and an examination of demographic patterns.
Collapsing focal segmental glomerulosclerosis in a patient with systemic lupus erythematosus.
Glomerulosclerosis (102) was the most frequently observed form of glomerular injury, occurring mainly in cases of chronic renal failure/ uremia.
Distribution of histological diagnosis and number of patients treated with immunosuppression Histological diagnosis Patients, Treated with n immunosuppression, n Lupus nephritis 31 27 (all classes) Focal segmental 25 20 glomerulosclerosis Mesangiocapillary 18 13 glomerulonephritis Post infections 7 4 glomerulonephritis RPGN/Cresentic 4 4 glomerulonephritis IgA nephropathy 3 0 Membranous 2 1 glomerulonephritis (non-lupus related) Mercury poisoning 1 0 Microscopic polyangiitis 1 0 Renal amyloidosis 1 1 Churg Strauss 1 1 HIV associated 1 0 nephropathy Non-specific glomerular 5 2 changes Table 4.
An increased renal RI value was found to be a marker for glomerulosclerosis and a predictor of global outcome in critically ill human patients [36, 37].
Fogo, "Causes and pathogenesis of focal segmental glomerulosclerosis," Nature Reviews Nephrology, vol.
2]S plays important and complex roles in renal physiology and pathophysiology, including the regulation of baseline hemodynamics and tubular properties [18, 19, 22], action as an oxygen sensor/transducer [28, 40], protection against renal I/R injury [21, 26, 41], attenuation of renal fibrosis [18, 42], and protection against glomerulosclerosis [28, 43].
Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis," Pediatric Nephrology, vol.
After several kidney biopsies in India in May 2011, it was established that she had Focal Segmental Glomerulosclerosis (FSGS), a nephrotic syndrome in children and adolescents and often a leading cause of kidney failure in adults.
About one quarter of nephrotic syndrome cases are caused by focal segmental glomerulosclerosis - scar tissue in the filtering unit of the kidney, called the glomerulus.
He has been diagnosed with focal segmental glomerulosclerosis and, in a statement on Twitter, Cole, 44, told fans that he contracted an airborne virus in June and suffered kidney failure.
Associated focal and segmental glomerulosclerosis in the acquired immunodeficiency syndrome.