glomerulosclerosis
Also found in: Dictionary, Acronyms, Encyclopedia, Wikipedia.
Related to glomerulosclerosis: focal segmental glomerulosclerosis
glomerulosclerosis
[glo-mer″u-lo-sklĕ-ro´sis]diabetic glomerulosclerosis (intercapillary glomerulosclerosis) a degenerative complication of diabetes mellitus in which there is glomerular mesangial expansion with either diffuse lesions or nodular (Kimmelstiel-Wilson) lesions; symptoms include albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy. The type with nodular lesions is also called Kimmelstiel-Wilson syndrome.
focal segmental glomerulosclerosis focal sclerosing lesions of the renal glomeruli, with proteinuria, hematuria, hypertension, and the nephrotic syndrome; it may be idiopathic or secondary to another condition. Called also focal glomerular sclerosis.
glo·mer·u·lo·scle·ro·sis
(glō-mer'yū-lō-sklē-rō'sis),Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes.
Synonym(s): glomerular sclerosis
[glomerulus + G. sklērōsis, hardness]
glomerulosclerosis
/glo·mer·u·lo·scle·ro·sis/ (glo-mer″u-lo-sklĕ-ro´sis) fibrosis and scarring resulting in senescence of the renal glomeruli.diabetic glomerulosclerosis intercapillary g.
focal segmental glomerulosclerosis a syndrome of focal sclerosing lesions of the renal glomeruli with proteinuria, hematuria, hypertension, and nephrosis, with variable progression to end-stage renal disease.
intercapillary glomerulosclerosis a degenerative complication of diabetes, manifested as albuminuria, nephrotic edema, hypertension, renal insufficiency, and retinopathy.
glomerulosclerosis
[-sklərō′sis]
Etymology: L, glomerulus, small ball; Gk, sklerosis, a hardening, osis, condition
a severe kidney disease in which glomerular function of blood filtration is lost as fibrous scar tissue replaces the glomeruli. The disease commonly follows an infection or arteriosclerosis.
)
Glomerulosclerosis
glomerulosclerosis
Nephrology A degenerative lesion of the renal glomeruli caused by ASHD or DM. See Kimmelsteil-Wilson disease.glo·mer·u·lo·scle·ro·sis
(glō-mer'yū-lō-skler-ō'sis)Hyaline deposits or scarring within the renal glomeruli, a degenerative process occurring in association with renal arteriosclerosis or diabetes mellitus.
[glomerulus + G. sklērōsis, hardness]
glomerulosclerosis
A kidney disease in which many glomeruli (see GLOMERULUS), previously damaged by inadequate blood supply or GLOMERULONEPHRITIS, become replaced by a non-functioning glassy (hyaline) material. It sometimes occurs without prior damage. The effects resemble those of the NEPHROTIC SYNDROME and kidney function gradually deteriorates. Kidney failure is a common outcome.glomerulosclerosis
progressive hyalinization such that glomeruli become shrunken, eosinophilic and hypocellular masses.
intercapillary glomerulosclerosis