Bilateral adrenal enlargement and calcification are seen and confined to the zona reticularis and inner fasciculata, with sparing of the zona glomerulosa
, outer fasiculata and medulla.
9) However, any organ or tissue with high lipid content will absorb carotenes and exhibit a bright-yellow or orange coloring, such as, the first 2 layers of the adrenal gland cortex (zona glomerulosa
and fasciculata, rich in aldosterone and lipids), the ovarian corpus luteum, the macula lutea in the eye (rich in lutein and zeaxanthin), organs rich in fat (pancreas, parotid gland), and adipose tissues.
Aldosterone is a mineralocorticoid hormone synthesized by the zona glomerulosa
of the adrenal cortex.
Evidence for a paracrine role of adrenomedullin in the physiological resetting of aldosterone secretion by rat adrenal zona glomerulosa
The development of the adrenal gland zona glomerulosa
in the rat: a morphological, immunohistochemical and biochemical study.
Potassium has a direct effect on the zona glomerulosa
of the adrenal glands for the secretion of aldosterone.
It is usually caused by a unilateral adenoma or rarely by carcinoma of zona glomerulosa
of adrenal gland (Javadi et al.
Gallo-Payet, "Role of MAPKs in angiotensin II-induced steroidogenesis in rat glomerulosa
cells," Molecular and Cellular Endocrinology, vol.
Incidences of nephropathy and, in the adrenal cortex, hypertrophy of the zona glomerulosa
and atrophy of the zona reticularis were significantly increased at 2,000x compared with controls (see Supplemental Material, Table S9), with severity increasing with dose for the adrenal observations.
The smaller outer glomerulosa
controls the Renin Angiotensin system.
In this study, the zona glomerulosa
appeared intact in the two rats found to have alteration of adrenal gland.
Se ha demostrado que las capas fasciculata y reticular de la glandula adrenal son las mas severamente comprometidas por el sangrado, mientras que el compromiso de la glomerulosa
es mas tardio o puede no presentarse (8).