These data describe up to one-year follow-up of patients treated with OMS721 in the glomerulonephropathy
Phase 2 clinical trial, which consisted of 12 weeks of treatment and 6 weeks of follow-up.
Proteinuria, or more specifically albuminuria, indicates glomerulonephropathy
These include acute renal failure, nephrotic syndrome with interstitial nephritis, chronic renal failure with or without glomerulonephropathy
, and papillary necrosis.
Goto, "A case of hepatitis C virus-associated glomerulonephropathy
presenting with MPO-ANCA-positive rapidly progressive glomerulonephritis," Japanese Journal of Nephrology, vol.
Cause of renal failure included: diabetes (32%), IgA nephropathy (12%), and hypertension (8%), other (48%--polycystic kidney disease, reflux nephropathy, glomerulonephropathy
Histopathological alterations were identified as focal nephropathy, glomerulonephropathy
, or tubuloi nterstitial lesions by Byung-il Yoon (College of Veterinary Medicine, Kangwon National University, Chuncheon, Korea).
An increase in glomerulonephropathy
nephrocalcinosis and fibrosarcoma of the skin was observed (Gur et al.
Gullain Barre syndrome has been observed in patients with membranous glomerulonephritis, focal segmental glomerulonephritis, extra membranous glomerulonephropathy
or nephrotic syndrome.
Non-infectious conditions for pyuria include calculous disease, stricture disease, neoplasm, glomerulonephropathy
, or intersitial cystitis.
One patient had focal mesangial proliferative glomerulonephropathy
, probably an early form of FSGS.
The primary renal lesion may have been glomerulonephropathy
, which was subsequently associated with tubular oxalosis as the secondary renal lesion.