glomerular filtration barrier

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Related to glomerular filtration barrier: Bowman's capsule, urinary space, Glomerular capillaries

glomerular filtration barrier

The structure of the renal glomerulus that prevents the loss of proteins in the urine, thereby preserving albumin and globulins in the plasma instead of letting them leach into the urine.

See also: barrier

References in periodicals archive ?

Glomerular filtration barrier. Curr Opin Nephrol Hypertens.

POST-EXERCISE PROTEINURIA IN THE CADETS TRAINED ON SPECIAL AERIAL GYMNASTICS INSTRUMENTS

Podocytes are the important components of the glomerular filtration barrier that prevents the excretion of albumin into the urine [21].

The glomerular filtration barrier is permanently exposed to hydrostatic pressure gradient across the capillaries, and therefore, the integrity of the interaction between the podocytes and the GBM is essential for the filtration to occur.

Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus

As podocytes play an important role in the structural and functional integrity of glomerular filtration barrier (GFB), any injury to the podocyte not only affects the structure of the podocyte or SD, but also disrupts the adjacent structures and consequently alters glomerular perm selectivity to the macromolecules in the blood.4,7

Understanding the pathogenesis of focal segmental glomerulosclerosis: morphology vs. molecules

Glomerular filtration barrier damage plays a critical role in proteinuria in chronic kidney disease [3], which contains fenestrated endothelium, glomerular basement membrane (GBM), and slit diaphragm (SD) [4].

Ameliorating adriamycin-induced chronic kidney disease in rats by orally administrated cardiotoxin from Naja naja atra venom

The most important event that precedes renal injury is an increase in permeability of plasma proteins such as albumin through a damaged glomerular filtration barrier. This results in excessive urinary albumin excretion (UAE) through the nephron.

Diabetes-Induced Reactive Oxygen Species: Mechanism of Their Generation and Role in Renal Injury

Previous studies have reported that podocytes are highly differentiated, insulin-dependent glomerular epithelial cells contributing to glomerular filtration barrier [2].

Metformin ameliorates podocyte damage by restoring renal tissue podocalyxin expression in type 2 diabetic rats