glomerular disease

glomerular disease

any of a group of diseases in which the glomerulus of the kidney is affected. Depending on the particular disease, there may be hyperplasia, atrophy, necrosis, scarring, or deposits in the glomeruli. The symptoms may be abrupt in onset or slowly progressive. Compare acute tubular necrosis. See also glomerulonephritis.

glomerular disease

Any of a large group of diseases that affect the glomerulus of the kidneys. They may be classified by clinical severity, by histological changes in the kidney, or by etiology. Etiological factors include primary glomerular disease; disease secondary to systemic disease, such as lupus erythematosus or polyarteritis; infectious disease such as streptococcal infection, malaria, syphilis, or schistosomiasis; metabolic disease such as diabetes or amyloidosis; toxins such as mercury, gold, or snake venom; serum sickness; and drug hypersensitivity.

Glomerular disease may also be associated with hereditary disorders (e.g., Alport's syndrome, Fabry's disease). See: glomerulonephritis; kidney; nephritis; nephrotic syndrome

The clinical consequences of glomerular diseases are associated both with the causes and with the extent of glomerular damage and typically include edema, proteinuria and hypertension.

glomerular disease (glōmer´yələr),

n a group of diseases in which the glomerulus of the kidney is affected.
References in periodicals archive ?
4],[5] Some hospitals have reported on the spectrum of pathological types seen in renal biopsies, but the overall situation regarding the common types of glomerular disease in China remains unclear.
Chemically induced glomerular disease, although much less common than the immune mediated forms of glomerulonephritis, occurs in variety of different ways (LoPachin, 2004; Takenaka et al.
While secondary glomerular disease (SGN) in our population was most commonly caused by lupus nephritis (LN).
Results: Most patients with proteinuria (91%, n=182) have glomerular disease.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized with immune complex formation and renal involvement of lupus and may include several kinds of pathological conditions, but mostly, it is associated with immune complex-induced glomerular disease.
WASHINGTON -- Another population-based study has found a link between severe psoriasis and kidney disease--this one discovering almost a fivefold increase in the risk of immunoglobulin A nephropathy (IgAN) and a doubling in the risk of glomerular disease.
Studies of patients presenting with persistent microscopic hematuria of unknown origin (PMHUO) indicate that those patients with glomerular disease exhibit deformed (dysmorphic) red cells, whereas patients with disease of the lower urinary tract express red cells that are normal and homogenous in shape and size.
Glomerular disease in patients with malignancy, although infrequent [1, 7-10], may be caused by viral infections and deposition of tumor antigens within the glomeruli, inducing antibody accumulation and activation of complement [8].
Among the topics are DNA damage and repair in vascular disease, the neural basis of long-distance navigation in birds, cortico-basal ganglia circuit function in psychiatric disease, and vascular growth factors and glomerular disease.
Glomerular disease in a Hispanic population: review of a regional renal biopsy database.
A multicenter cross-sectional study of circulating soluble urokinase receptor in Japanese patients with glomerular disease," Kidney International, vol.